Báo cáo sinh học: "Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance" ppt
... functional characterization of
an insulin- binding protein in invertebrates. We have
identified Imp-L2 as a secreted antagonist of IIS in
Drosophila. Given the sequence homology of their Ig
domains, ... genetic analyses of
IIS in Drosophila and Caenorhabditis elegans have not
revealed a functional insulin- binding protein so far.
Here, we report the identification...
... 24 h before virus inoculation. Bronchoalveolar lavage (BAL) and serum samples
were obtained at days 1, 5 (acute) and 28 (long-term) post inoculation and analyzed with a multiplex
assay (Beadlyte ... review, and MBR per-
forming experiments; JC Luminex data analysis and inter-
pretation. PK and HSJ data interpretation; OR project
design, experimental analyses and interpretation...
... TGCAGCTTCAAGTAGGCTGAGGAA
3’ ). b-actin (forward, 5’ CTGGCACCACACCTTCTA-
CAATGA 3’ and reverse, 5’ TTAATGTCACGCAC-
GATTTCCCGC 3’ ). For each pair of primers, the
following protocol was applied. Initial ... in
malignant and benign prostate tissue. A: Immunohistochemical
staining of periostin in PCa and BPH. Negative epithelial and stromal
periostin expression in BPH (a) an...
... aassssoocciiaattiioonn mmaappppiinngg??
Both methods have advantages and
disadvantages. Linkage mapping,
particularly in controlled crosses (as
opposed to, say, human families), has
the advantage of increased power ... the rapid identification of
large numbers of polymorphisms in
parental strains used in linkage-
mapping studies, or a sample of
individuals from a populatio...
... CSIC-Universidad de Valladolid, Spain
2 Program of In ammation, In ammatory and Infectious Disease Center, and Program of Signal Transduction, Burnham Institute for Medical
Research, La Jolla, CA, USA
3 ... Inc. (Santa Cruz, CA, USA), anti-cullin 3 was
from Abcam (Cambridge, UK), and mAbs against b-actin,
PHA, FLAG M2 mAb and PMA were from Sigma Chemical
Co. (St Louis, MO, USA...
... roles in
initial evaluation and staging of patients, ART initiation,
and patient monitoring [3].
As nurses are becoming increasingly central points of con-
tact for clinical care of people living ... text-
books and teaching materials and little classroom space),
variable quality of teaching with few classroom instructors
prepared to educate, and few clinical instructors...
... exert and maintain an effort
towards attaining organizational goals [9].
Although it is likely that motivation influences perform-
ance directly and mediates or modifies the effect of inter-
ventions ... Survival in
Uganda. International Journal of Health Planning and Management
2003, 18:329-342.
33. Krogstad U, Hofoss D, Veenstra M, Hjortdahl P: Predictors of job
satisfaction...
... needed a substantial revision
to allow a clear-cut interpretation of our findings. As
stated in the results section, hypoxia per se induces i)
down-regulation of miRNA-44 9a/ b and also miRNA-
51 8a- 3p ... Bock.Oliver@MH-Hannover.de
1
Institute of Pathology, Hannover Medical School, Carl-Neuberg-Strasse 1,
30625 Hannover, Germany
Full list of author information is available...
... cells in acute renal injury: ca ira. Curr Opin
Pharmacol 2006, 6(2):176-183.
12. Miyahara Y, Nagaya N, Kataoka M, Yanagawa B, Tanaka K, Hao H, Ishino K,
Ishida H, Shimizu T, Kangawa K, et al: Monolayered ... tra nsplantation has been used in
clinical trials and animal models to treat musculoskeletal
injuries, improve cardiac function in cardiovascular
dis eas e and ameliorate the se...
... following primers were used:
bcl-2 forward 5’ -GTGAACTGGGGGAGG ATTGT-3’
and reverse 5’-GGAGAAATCAAACAGAGGCC-3’ ;
GAPDH forward 5’-CCAAGGTCATCCATGACAAC-3’
and reverse 5’ -TTACTCCTTGGAGGCCATGT-3’ ... Baldi A: Patterns of tumor response in canine and feline cancer
patients treated with electrochemotherapy: preclinical data for the
standardization of this treatment in pets and...