Báo cáo sinh học: "Does gene dosage really matter" ppsx

... compensated, genes that must be differentially expressed in males and females, and genes for which dosage really does not matter. Genes that must be dosage compensated, because they lie in dosage- sensitive pathways, ... less efficient dosage compensation in birds. One is that dosage differences for many genes really are not as important as we have believed. Another is that diffe...

Ngày tải lên: 06/08/2014, 18:21

... of Consultations in General- Practice in Sweden – Views of Doctors and Patients. Family Practice 1989, 6:130-134. 33. Britt H, Valenti L, Miller G: Time for care. Length of general practice consultations ... documentation and had generally fewer working hours per day, compared to physicians working at public hospitals. This leads to the question as to whether public hospitals have general org...

Ngày tải lên: 18/06/2014, 17:20

... However, the discrepancy of pathogenesis and clinical manifestations of these viruses strongly suggests that these viruses must have different receptor(s) and pathogenesis on human. Even so, identification ... char- acterization of receptor on mosquito cells is the prologue to final elucidation of flavivirus pathogenesis on human. To confirm that HSC70 is a receptor for JEV on C6/36 mosquito...

Ngày tải lên: 18/06/2014, 18:20

... is 519 bp. The mouse CFTR gene was used as an internal control. The forward primer corresponds to the mouse cystic fibrosis trans- membrane conductance regulator (CFTR) gene exon 2 (DL1286, 5’-CATATACCAAGCCCCTTCT ... GCT). The reverse primer corresponds to the mouse CFTR gene intron 2 (DL1287, 5’ - TGCATCACTTTTAAATG- GAACCTC). The expected mouse CFTR gene amplicon size is 160 bp. West...

Ngày tải lên: 18/06/2014, 22:20

... dehydrogenase (GAP) gene and the β-actin (Act) gene were used as con- trol genes in classical molecular methods for RNA detec- tion. Recently, evidence accumulated that especially these two genes, GAP ... of 13 potential reference genes in 16 different tis- sues and presented more suitable genes like the RNA polymerase II gene [5]. However, an evaluation of refer- ence genes in virus in...

Ngày tải lên: 18/06/2014, 22:20

... Hans.Ellegren@ebc.uu.se Students of population genetics learn from their textbooks that levels of genetic diversity are determined by the rate of mutation (the number of new mutations per nucleotide site and generation) and ... more new genetic variants and a large population is less sensitive to random loss of variants by genetic drift. It therefore came as a surprise when it was reported a...

Ngày tải lên: 06/08/2014, 19:20

... species, so to what extent does this generalization still hold? Is it possible (or meaningful) to generalize - have ecdysozoans in general lost more genes than lophotrochozoans or deuterostomes, ... perhaps lophotrochozoans in general) are less derived than the insects and nematodes investigated so far. One focus of the paper [1] was patterns of gene sharing and gene loss between Po...

Ngày tải lên: 06/08/2014, 19:21

... and several clusters of coordinated gene expres- sion were highlighted. Most clusters contained genes with a variety of functions, although some co-regulated genes were functionally related. ... there were many genes of unknown function co-regulated with genes of known function. This clustering can lead to testable hypotheses for examining the role of hypothetical genes. Regulatory ......

Ngày tải lên: 06/08/2014, 19:21

... spongiform encephalopathies and genetics, Vet. Res. Commun. 27 (Suppl. 1) (2003) 31–38. [3] Aguzzi A., Prion diseases of humans and farm animals: epidemiology, genetics, and pathogenesis, J. Neurochem. ... prion protein gene and their association to BSE infection, FASEB J. 21 (2007) 1547–1555. [15] Kurosaki Y., Ishiguro N., Horiuchi M., Shinagawa M., Polymorphisms of caprine PrP gene dete...

Ngày tải lên: 14/08/2014, 13:21

... based on gene frequency (BGF) where both conditional means and variances are modeled as a function of the conditional gene frequencies at the QTL. The parameters in this model include these gene ... models is that in the gene frequency model residual variances are het- erogeneous (see equation 18), whereas in the regression model residual variances are assumed homogeneous. Another dif...

Ngày tải lên: 14/08/2014, 13:21