Báo cáo sinh học: "Nuclear localization is required for Dishevelled function in Wnt/ -catenin signaling" pps

... effect of HFE binding to TfR1 is to lower the affinity of the receptor for transferrin [15]. This most likely reflects the existence of overlapping HFE and transferrin- binding sites on the receptor ... 3229 N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface...

Ngày tải lên: 06/03/2014, 22:21

... Cellular localization of human spermine oxidase FEBS Journal 275 (2008) 279 5–2 806 ª 2008 The Authors Journal compilation ª 2008 FEBS 2801 Nuclear localization of human spermine oxidase isoforms – possible ... decreases in intracellular spermine pools and increased spermidine levels in SMO1 and SMO5 cells. These changes in spermine and spermid...

Ngày tải lên: 07/03/2014, 05:20

... 1 of 5 (page number not for citation purposes) Virology Journal Open Access Short report Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage ... not for citation purposes) efficient replication of herpesviruses [7-13], bovine leuke- mia virus [14], and rotavirus [15]. In case of human cytomegal...

Ngày tải lên: 18/06/2014, 18:20

... region similar to that seen in the rodent-borne hantaviruses. Although the function of this motif is unclear for the hantaviruses, it has been shown with other viruses to be a redox site and play ... [9]. No further virus isolates have been obtained, and it remains unclear whether the Asian house shrew is the TPM virus primary reservoir or merely represents a...

Ngày tải lên: 18/06/2014, 18:20

... BioMed Central Page 1 of 14 (page number not for citation purposes) Virology Journal Open Access Research Intracellular localization of Crimean-Congo Hemorrhagic Fever (CCHF) virus glycoproteins Sebastian ... Charac- teristics of Crimean-Congo hemorrhagic fever virus (Xin- jiang strain) in China. Am J Trop Med Hyg 1985, 34(6):1179-1182. 18. Hoogstral H: The epide...

Ngày tải lên: 19/06/2014, 08:20

... 20 àm. GFP Phase Merge V E6* I E6 E6MT A V E6* I E6 E6MT GFP Phase Merge B Co -localization of E6s and E6AP in 293T (A) and HaCaT (B)Figure 3 Co -localization of E6s and E6AP in 293T (A) and HaCaT ... previous reports of HPV18 E6 localization [17,18]. However, the localizations of E6 and E6* I proteins are different than one previous study of HPV16 E6 [19] which...

Ngày tải lên: 19/06/2014, 08:20

... s2 ssRNA [10]. These 96 nucleotides and 284 from the wt s2 at the 3' end of an engineered ssRNA are sufficient to direct incorporation of an s2 ssRNA into the reovirus serotype 3 genome. The required ... viral particles. The work presented here builds on these findings and presents the results of an analysis of the required 3' flanking...

Ngày tải lên: 19/06/2014, 08:20

... CACACCCTGTAGAGGGC TCTCCAG C33 5A 1044R-C /A CCTTTCTTATCAGC CACCCTGTAGAG F35 7A REP/F -A GGAATACAGC TGGCAAGGC D36 3A REP/D -A TGATCCTGGG CGTATGCGC P39 9A MUTPMV-1236R GCCCCAACTAATGC ATTGGTCACTAG W40 5A REP/W -A CCAAGCAGTCGC ATTGGCCCC a. ... F1-313-F2 GGAACCCCAGCA AACTCGTTCTTTGC P31 7A P31 7A- 989R CTGTGGGTTTTGC AACCCCAGCG N32 3A N32 3A- 1007R CAGCCAACTGGGC AGCCTCTGTG L32 5A L32 5A...

Ngày tải lên: 19/06/2014, 08:20

... whereas Frodo, another Dsh-binding protein, is required for Wnt/ -catenin signaling in the nucleus [14]. These interactions may take place in various cellular compartments, linking spe- cific activities ... containing Wnt3a results in nuclear accumulation of endogenous Dsh protein. Conclusions: These findings suggest that nuclear localization of Dsh is required for i...

Ngày tải lên: 06/08/2014, 18:21

... ratios than A genes. In (b) the panel on the far right shows distributions for brain of individual chromosomes containing more than 50 genes. In all panels in (a) and (b) the rightmost bin (at ... constitutively higher levels in one sex compared with the other. Sex-chromosome dosage compensation is surprisingly ineffective in birds, suggesting that some genomes can do with...

Ngày tải lên: 06/08/2014, 18:21

... variability. From an examination of nearly 4 000 curves we observed that they generally have a regular sigmoidal shape, with an inflexion point at about 10 years and an ... a global estima- tion of the position parameter (h 0) yielded Original article Choice of a model for height-growth curves in maritime pine F Danjon JC Hervé 1 INR...

Ngày tải lên: 08/08/2014, 19:21

... transcribed in pollen and sperm cells. Therefore, we decided to investigate the role of glutathione synthesis for pollen germination in vitro in Arabidopsis thaliana accession Col-0 and in the glutathione ... glutathione depletion in pollen grains triggered disturbances in auxin metabolism which led to inhibition of pollen germination. Conclusions: This study...

Ngày tải lên: 11/08/2014, 11:21

... regulating mucus overproduction in smoke inhalation injury. In the present study, MUC5AC protein expression was increased within 4 hour after 15 min smoke inhalation. The expression was sustained ... and also in a combined burn and smoke inhalation injury model [6] , but the mechanism by which smoke damages the airway still remains unclear. In our mouse model of smo...

Ngày tải lên: 12/08/2014, 13:22

... prolifera- tion of human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2006. 26. Frid MG, Moiseeva EP, Stenmark KR: Multiple phenotypically dis- tinct smooth muscle cell populations exist in the ... E: Distribution of phenotypically disparate myocyte subpopula- tions in airway smooth muscle. Can J Physiol Pharmacol 2005, 83:104-116. 34. Halayko AJ, Rector E, Ste...

Ngày tải lên: 12/08/2014, 16:20

... pre-weaning growth is the same trait in single- and twin-reared lambs; i.e. to determine whether the number of lambs suckling affects the var- iance components that act on pre-weaning growth, 2) whether ... used for this study. In this study, we focused on the possible heter ogeneity of variance components for pre-weaning growth in sheep due to...

Ngày tải lên: 14/08/2014, 13:21