Báo cáo sinh học: "RNAi and the shape of things to come" ppsx

... lot of the apparent complexity in cell biology is a product of over-expression studies, and loss -of- function data can clarify some of these situations.” And then we will have to go back to the ... a large number of interactions between the cell and the extracellular matrix, as well as the internal cytoskeleton that is composed of networks of actin filaments...

Ngày tải lên: 06/08/2014, 18:20

... conceived and coordinated the study and drafted the paper; PM carried out the mathematical analysis; AT, DK, NS, NP and ET collected data and assisted in the development of the draft of the manuscript; ... interest towards their training, on the merit of their CME activi- ties, on the responsibilities and time given to them for patient care and on the ove...

Ngày tải lên: 18/06/2014, 17:20

... better understand the mechanism of action of HRSV neutralizing antibodies and the impact of resistance to these antibodies upon the fusion activity of the F protein. A summary of these results is ... mutagenesis of the HRSV F protein. AD and RS participated in the design, oversight of the conduct of the experiments, and interpretation of the results...

Ngày tải lên: 18/06/2014, 18:20

... inactivation of Tax-2 lead- ing to the inhibition of HTLV-2 retrovirus replication. Further studies of subcellula r localization unveiled the co-localization of Tax-2 and CIITA both in the cyto- plasm and ... role in the home- ostasis of the immune system. They present peptides to the antigen receptor of CD4+ T cells (TH), whose acti- vation is required to tr...

Ngày tải lên: 18/06/2014, 22:20

... typically target the inflammatory response, the mechanism of fibrosis is poorly understood and there are few effective thera- pies. For these reasons, and knowing the multitude of pathways that ... by the RNase III Drosha to produce precur- sor miRNAs of 70 nucleotides. These are then trans- ported to the cytoplasm where they are further processed by another RNase III e...

Ngày tải lên: 15/03/2014, 11:20

... and poor high school preparation. Students knew that they would be needed in the public sector, and that this represented an opportunity to contribute to the welfare of the population. Nevertheless, ... compares the socioeconomic profile of medical students registered at the Faculty of Medicine of Universidade Eduardo Mondlane (FM -UEM), Maputo, for the years 1998/...

Ngày tải lên: 18/06/2014, 17:20

... it’s so bad they want to get out of t here and if their country is forcing them to stay - that’s not good for the individual.” The literature also suggests that the migration of health professionals is ... Political, Economic, Social and Cultural Rights. Report of the Special Rapporteur on the right of everyone to the enjoyment of the highest attainable stand...

Ngày tải lên: 18/06/2014, 17:20

... versa. Neither of the other two viruses transmitted either way. Sequence analysis of the HA1 gene of the Ohio strain showed one amino acid change (D to A) at residue 190 of the receptor binding ... contribute to the transmission of these viruses between swine and turkeys. The use of the reverse genetics and site directed mutagenesis could also be helpful in d...

Ngày tải lên: 18/06/2014, 18:20

... markers [27]. Therefore, the effect of anti-asialo GM1 and anti-NK1.1 antibodies on host resistance to HSV-1 may be due, at least in part, to their capacity to blunt the T cell response to viral infections ... abundance does not impair the capacity of a scid mouse to limit HSV-1 spread from the site of inoculation. Role of peripheral WBCs in innate resistance to...

Ngày tải lên: 19/06/2014, 08:20

... For example, because of such highways of gene sharing these types of analyses group members of the order Thermotogales with the Firmicutes, and the members of the 54.2 Journal of Biology 2009, Volume ... represents neither the history of any individual gene, nor the history of the organism as a whole. Another problem with supermatrix and supertree analyses is...

Ngày tải lên: 06/08/2014, 19:20