Chapter 128. Pneumococcal Infections (Part 7) doc
... complicated infections. A recent study reported identical rates of clinical and bacteriologic cure with a 10-day course of amoxicillin and a single dose of azithromycin (30 mg/kg). Chapter 128. Pneumococcal ... dose of azithromycin (30 mg/kg). Chapter 128. Pneumococcal Infections (Part 7) Antibiotic Regimens Otitis Media (Table 128- 4) Current treatment recomme...
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... polysaccharides. Epidemiology Chapter 128. Pneumococcal Infections (Part 1) Harrison's Internal Medicine > Chapter 128. Pneumococcal Infections Pneumococcal Infections: Introduction Streptococcus ... residues serve as a site of attachment for potential virulence factors, such as pneumococcal surface protein A (PspA) and pneumococcal surface adhesin A (P...
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Chapter 128. Pneumococcal Infections (Part 2) pptx
... circulation; in the absence of antibody, however, only the slow passage of blood Chapter 128. Pneumococcal Infections (Part 2) Nonimmunologic Mechanisms Nonimmunologic mechanisms that protect ... without spleens tend to develop overwhelming pneumococcal disease that rapidly progresses to death. Table 128- 1 Conditions that Commonly Predispose to Pneumococcal Infection...
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Chapter 128. Pneumococcal Infections (Part 3) potx
... pneumoniae is the most common or second most Chapter 128. Pneumococcal Infections (Part 3) Specific Infections Caused by S. Pneumoniae S. pneumoniae causes infections of the middle ear, sinuses, ... individual case. Infections listed after meningitis in Table 128- 2 are uncommon or rare. Table 128- 2 Most Common Infections Caused by Streptococcus Pneumoniae in Adul...
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Chapter 128. Pneumococcal Infections (Part 4) pot
... (hemoglobin level, <10 g/dL) is documented in 25% of cases. The peripheral-blood white blood cell (WBC) count exceeds 12,000/µL in the great majority of patients with pneumococcal pneumonia. A low ... volume of fluid to allow aspiration, and in only a minority of these patients is empyema documented. Figure 128- 1 ... syncytial virus Microaerophilic and anaerobic mouth A...
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Chapter 128. Pneumococcal Infections (Part 5) pot
... yield S. pneumoniae in ~25% of patients hospitalized for pneumococcal pneumonia. Figure 128- 2 Gram-stained sputum from a patient with pneumococcal pneumonia shows polymorphonuclear cells ... infection. A case of pneumococcal endocarditis is seen every few years at large tertiary-care hospitals. Purulent pericarditis, occurring as a separate entity or together with endocardi...
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Chapter 128. Pneumococcal Infections (Part 6) pdf
... resistance is Chapter 128. Pneumococcal Infections (Part 6) Pneumococcal Infections: Treatment Antibiotic Susceptibility β-Lactam antibiotics, the cornerstone of therapy for serious pneumococcal ... >90% of pneumococcal isolates in the United States are susceptible to clindamycin. Rates of doxycycline resistance are similar to those observed for macrolides. One-thir...
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Chapter 128. Pneumococcal Infections (Part 8) pot
... higher in others; high-dose amoxicillin remains the best option worldwide. Chapter 128. Pneumococcal Infections (Part 8) Acute Sinusitis Just as the pathogenesis and microbial etiology ... Treatment failure resulting in bacteremic disease due to macrolide-resistant isolates has been amply documented in patients treated empirically with azithromycin. As noted above, rates o...
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Chapter 128. Pneumococcal Infections (Part 9) potx
... clear Chapter 128. Pneumococcal Infections (Part 9) Inpatient Therapy Pneumococcal pneumonia is readily treatable with β-lactam antibiotics. The conventional dosages shown in Table 128- 5 ... should be administered for 5– 7 days after defervescence or for a total of 10 days. Endocarditis Pneumococcal endocarditis is associated with rapid destruction of heart valves. Pen...
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Chapter 128. Pneumococcal Infections (Part 10) ppsx
... Chapter 128. Pneumococcal Infections (Part 10) Prevention Capsular Polysaccharide Vaccine The pneumococcal capsular polysaccharide vaccine administered ... case-control study showed a protection rate of 85% lasting ≥5 years in adults <55 years old (Table 128- 7). The level and duration of protection decreased with advancing age. Other studies have suggested ... broad...
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