Chapter 128 Pneumococcal Infections (Part 7) doc
Chapter 128. Pneumococcal Infections (Part 7) doc
... complicated infections. A recent study reported identical rates of clinical and
bacteriologic cure with a 10-day course of amoxicillin and a single dose of
azithromycin (30 mg/kg).
Chapter 128. Pneumococcal ... dose of
azithromycin (30 mg/kg).
Chapter 128. Pneumococcal Infections
(Part 7)
Antibiotic Regimens
Otitis Media
(Table 128- 4) Current treatment recomme...
Chapter 128. Pneumococcal Infections (Part 1) H pot
... polysaccharides.
Epidemiology
Chapter 128. Pneumococcal Infections
(Part 1)
Harrison's Internal Medicine > Chapter 128. Pneumococcal Infections
Pneumococcal Infections: Introduction
Streptococcus ... residues serve as a site of
attachment for potential virulence factors, such as pneumococcal surface protein A
(PspA) and pneumococcal surface adhesin A (P...
Chapter 128. Pneumococcal Infections (Part 2) pptx
...
circulation; in the absence of antibody, however, only the slow passage of blood
Chapter 128. Pneumococcal Infections
(Part 2)
Nonimmunologic Mechanisms
Nonimmunologic mechanisms that protect ... without spleens tend
to develop overwhelming pneumococcal disease that rapidly progresses to death.
Table 128-
1 Conditions that Commonly Predispose to Pneumococcal
Infection...
Chapter 128. Pneumococcal Infections (Part 3) potx
... pneumoniae is the most common or second most
Chapter 128. Pneumococcal Infections
(Part 3)
Specific Infections Caused by S. Pneumoniae
S. pneumoniae causes infections of the middle ear, sinuses, ... individual case.
Infections listed after meningitis in Table 128- 2 are uncommon or rare.
Table 128- 2 Most Common Infections Caused by
Streptococcus
Pneumoniae in Adul...
Chapter 128. Pneumococcal Infections (Part 4) pot
... (hemoglobin level, <10 g/dL) is documented in 25% of cases. The
peripheral-blood white blood cell (WBC) count exceeds 12,000/µL in the great
majority of patients with pneumococcal pneumonia. A low ... volume of fluid to allow
aspiration, and in only a minority of these patients is empyema documented.
Figure 128- 1
... syncytial virus
Microaerophilic and anaerobic mouth
A...
Chapter 128. Pneumococcal Infections (Part 5) pot
...
yield S. pneumoniae in ~25% of patients hospitalized for pneumococcal
pneumonia.
Figure 128- 2
Gram-stained sputum from a patient with pneumococcal pneumonia
shows polymorphonuclear cells ... infection. A case of
pneumococcal endocarditis is seen every few years at large tertiary-care hospitals.
Purulent pericarditis, occurring as a separate entity or together with endocardi...
Chapter 128. Pneumococcal Infections (Part 6) pdf
... resistance is
Chapter 128. Pneumococcal Infections
(Part 6)
Pneumococcal Infections: Treatment
Antibiotic Susceptibility
β-Lactam antibiotics, the cornerstone of therapy for serious pneumococcal ... >90% of pneumococcal isolates in the United
States are susceptible to clindamycin. Rates of doxycycline resistance are similar
to those observed for macrolides. One-thir...
Chapter 128. Pneumococcal Infections (Part 8) pot
... higher in others; high-dose
amoxicillin remains the best option worldwide.
Chapter 128. Pneumococcal Infections
(Part 8)
Acute Sinusitis
Just as the pathogenesis and microbial etiology ... Treatment failure resulting in bacteremic
disease due to macrolide-resistant isolates has been amply documented in patients
treated empirically with azithromycin. As noted above, rates o...
Chapter 128. Pneumococcal Infections (Part 9) potx
... clear
Chapter 128. Pneumococcal Infections
(Part 9)
Inpatient Therapy
Pneumococcal pneumonia is readily treatable with β-lactam antibiotics. The
conventional dosages shown in Table 128- 5 ... should be administered for 5–
7 days after defervescence or for a
total of 10 days.
Endocarditis
Pneumococcal endocarditis is associated with rapid destruction of heart
valves. Pen...
Chapter 128. Pneumococcal Infections (Part 10) ppsx
... Chapter 128. Pneumococcal Infections
(Part 10)
Prevention
Capsular Polysaccharide Vaccine
The pneumococcal capsular polysaccharide vaccine administered ... case-control study showed a
protection rate of 85% lasting ≥5 years in adults <55 years old (Table 128- 7). The
level and duration of protection decreased with advancing age. Other studies have
suggested ... broad...
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