Chapter 137. Gonococcal Infections (Part 9) pps

... gait With Chapter 063. Chromosome Disorders (Part 9) Microdeletion Syndromes The term contiguous gene syndrome refers to genetic disorders that mimic a combination of single-gene disorders. ... abnormality involves a deletion of a part of the short arm of chromosome 11 (11p13), which typically is detectable on well-banded chromosome preparations. In MDS, a disorder...

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... of ovarian germ cell tumors: A gynecologic oncology group study. Gynecol Oncol 105:687, 2007 [PMID: 17355890] Chapter 093. Gynecologic Malignancies (Part 9) Clinical Presentation Molar ... Gynecologic Oncology, 4th ed, WJ Hoskins et al (eds). Philadelphia, Lippinc ott Williams & Wilkins, 2005, pp 895–987 Randall ME et al: Uterine cervix, in Principles and Practi...

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... proteases (PCCs), which further aggravates the disease. Replacement of Coagulation or Fibrinolysis Inhibitors Drugs to control coagulation such as heparin, antithrombin III (ATIII) concentrates, ... replacement with FFP or PCC is required. PCC should be avoided in patients with severe underlying liver disorders due to high risk of thrombosis. The reversal of excessive anticoagulan...

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... Chapter 136. Meningococcal Infections (Part 2) In the United States, the attack rate for sporadic meningococcal disease is ~1 case per 100,000 ... pathogenesis. Figure 136-1 Meningococcal disease pathogenesis, susceptibility, and severity. After human-to-human transmission, environmental factors (smoking, co- infections) , polymorphisms ... adults (<1 case...

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... immunity (decreased transmission and colonization). Chapter 136. Meningococcal Infections (Part 7) Complications Patients with meningococcal meningitis may develop cranial nerve palsies, ... clinical clues help the physician distinguish the patient with early meningococcal disease from patients with other acute systemic infections. The most useful clinical finding is...

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... genes.' BMC Genomics 7:128, 2006 [PMID: 16734888] Chapter 136. Meningococcal Infections (Part 9) Antimicrobial Chemoprophylaxis The attack rate for meningococcal disease among household or other ... 9472667] Rosenstein NE et al: Meningococcal disease. N Engl J Med 344:1378, 2001 [PMID: 11333996] Westendorp RGJ et al: Genetic influence on cytokine production and...

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... Chapter 137. Gonococcal Infections (Part 1) Harrison's Internal Medicine > Chapter 137. Gonococcal Infections Definition Gonorrhea is a sexually ... variants. In a fallopian tube explant model, pili mediate gonococcal attachment to nonciliated columnar epithelial cells. This event initiates gonococcal phagocytosis and transport through these ... and...

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... as well as CD8+ T lymphocytes is seen in individuals Chapter 137. Gonococcal Infections (Part 2) Opacity-Associated Protein Another gonococcal surface protein that is important in adherence ... against neisserial infections is best illustrated by the predisposition of persons deficient in terminal complement components (C5 through C9) to recurrent bacteremic gonococcal...

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... and seminal vesiculitis. Balanitis may develop in uncircumcised men. Chapter 137. Gonococcal Infections (Part 3) Gonococcal Resistance to Antimicrobial Agents It is no surprise that N. ... and diplococci (Fig. 137-1). The clinical manifestations of gonococcal urethritis are usually more severe and overt than those of nongonococcal urethritis, including urethritis cau...

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... Chapter 137. Gonococcal Infections (Part 4) Gonococcal Infections in Females Gonococcal Cervicitis Mucopurulent cervicitis is the most ... cities since the 1990s. Gonococcal isolates from the rectum of MSM tend to be more resistant to antimicrobial agents than are gonococcal isolates from other sites. Gonococcal isolates with ... plated directly onto gonococca...

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... tetracycline) prevents ophthalmia neonatorum but is not effective for its treatment, Chapter 137. Gonococcal Infections (Part 5) Ocular Gonorrhea in Adults Ocular gonorrhea in an adult usually results ... possibility of sexual abuse. Gonococcal vulvovaginitis is the most common manifestation of gonococcal infection in children beyond infancy. Anorectal and pharyngeal...

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... joints are occasionally involved. Most patients who develop gonococcal septic arthritis do so Chapter 137. Gonococcal Infections (Part 6) The clinical manifestations of DGI have sometimes ... et al: Disseminated gonococcal infection. Ann Intern Med 74:979, 1971.) Figure 137-3 Distributions of joints with arthritis in 102 patients with disseminated gono...

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... cervical swab samples are assessed by culture and other non- NAATs. Chapter 137. Gonococcal Infections (Part 7) Gonococcal Infections in HIV-Infected Persons The association between gonorrhea ... (PCR) more commonly in ejaculates from HIV-positive men with gonococcal urethritis than in those from HIV-positive men with nongonococcal urethritis. PCR positivity diminis...

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... infection is not ruled out: Azithromycin (1 g PO, single dose) or Chapter 137. Gonococcal Infections (Part 8) Gonococcal Infections: Treatment Treatment failure can lead to continued transmission ... single-dose regimens have been developed for uncomplicated gonococcal infections. The updated 2006 treatment guidelines for gonococcal infections from the Centers...

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... simulates in vivo effects. J Infect Dis 179:124, 1999 [PMID: 9841831] Chapter 137. Gonococcal Infections (Part 9) Single-dose regimens of the third-generation cephalosporins ceftriaxone ... recurrent or persistent gonorrhea or chlamydial infections. N Engl J Med 352:676, 2005 [PMID: 15716561] Hook EW III, Holmes KK: Gonococcal infections. Ann Intern Med 102:229, 19...

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