Chapter 136 Meningococcal Infections (Part 5) ppt

... acquiring meningococcal disease in childhood. Alleles that decrease MBL synthesis have been associated with increased risk in the few studies reported to date. Chapter 136. Meningococcal Infections ... Meningococcal Infections (Part 5) Host Defense Mechanisms Preventing meningococcal growth in blood requires bactericidal and opsonic antibodies, complement, and phago...

Ngày tải lên: 08/07/2014, 02:20

... epidemics of serogroup W-135 meningococcal disease occurred in association with the Muslim pilgrimage to Mecca (the Hajj) and in the meningitis belt of sub-Saharan Africa. meningococcal strains ... (LOS, immunotype). Thus, for example, the meningococcal strain designation B:2b:P1.5:L3,7,9 reflects the serogroup (B), serotype (2b), serosubtype (P1 .5), and immunotype (L3,7,9). Meni...

Ngày tải lên: 08/07/2014, 02:20

... and in family members of patients found to have a complement deficiency. Chapter 136. Meningococcal Infections (Part 8) Patients with fulminant meningococcemia often experience diffuse ... introduction of herd immunity. Memory response to meningococcal polysaccharide also appears to be an important effect of the conjugate vaccines. Meningococcal conjugate vaccines are...

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... Chapter 136. Meningococcal Infections (Part 2) In the United States, the attack rate for sporadic meningococcal disease is ~1 case per 100,000 ... pathogenesis. Figure 136- 1 Meningococcal disease pathogenesis, susceptibility, and severity. After human-to-human transmission, environmental factors (smoking, co- infections) , polymorphisms ... adults (<1 case p...

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... for this serogroup. Outer-Membrane Proteins Chapter 136. Meningococcal Infections (Part 3) Outer-Membrane Components Associated with Virulence Meningococcal strains are characterized by the ... properties promote meningococcal transmission, spread, and survival externally and within intracellular compartments such as phagocytic vacuoles. Except in serogroup A, the major...

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... Meningitis Chapter 136. Meningococcal Infections (Part 4) Association of Virulence Mechanisms with Specific Meningococcal Infections Specific disease manifestations of meningococcal infections ... potential site of meningococcal entry into the CSF. Meningococcal pili may bind CD46, a complement-regulatory protein that is expressed by the choroid plexus and menin...

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... endocarditis. Figure 136- 4 Chapter 136. Meningococcal Infections (Part 6) Clinical Manifestations Upper Respiratory Tract Infections Although many patients who develop meningococcal meningitis ... immune complex deposition. Primary meningococcal pneumonia occurs principally in adults, often in military populations, and is often due to serogroup Y. While meningoco...

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... immunity (decreased transmission and colonization). Chapter 136. Meningococcal Infections (Part 7) Complications Patients with meningococcal meningitis may develop cranial nerve palsies, ... patient with early meningococcal disease from patients with other acute systemic infections. The most useful clinical finding is the petechial or purpuric rash (see Fig. 52 -5), but...

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... genes.' BMC Genomics 7:128, 2006 [PMID: 16734888] Chapter 136. Meningococcal Infections (Part 9) Antimicrobial Chemoprophylaxis The attack rate for meningococcal disease among household or other ... 9472667] Rosenstein NE et al: Meningococcal disease. N Engl J Med 344:1378, 2001 [PMID: 11333996] Westendorp RGJ et al: Genetic influence on cytokine production and fat...

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... Chapter 063. Chromosome Disorders (Part 5) Chromosome segregation in meiosis. A. In meiosis I, each of the 23 pairs

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