... alone and with bacteria—have been
rhinovirus, parainfluenza virus, and influenza virus. Bacterial causes of sinusitis
have been better described. Among community-acquired cases, S. pneumoniae and ... associated with bacteria found in the hospital environment,
including S. aureus, Pseudomonas aeruginosa, Serratia marcescens, Klebsiella
pneumoniae, and Enterobacter species. Often,...
...
CT, MRI, and positron emission tomography have benefited patients by
supplanting older, more invasive approaches and opening new diagnostic vistas.
Cognizant of their capabilities and the rapidity ... the context of the patient's condition and other test results.
The development of technically improved imaging studies with greater
sensitivity and specificity is one of the...
... strengthened and brought into force in May 2007.
Even as attention to and resources for health problems in resource-poor
settings grow, the lack of coherence in and among global health institutions ... each year. New research, new
policies, and new funding mechanisms were called for. Some of the requisite
Chapter 002. Global Issues in Medicine
(Part 2)
The optimism b...
... membrane of any cell, including enterocytes
and hepatocytes, is a combination of passive diffusion and active transport,
mediated by specific drug uptake and efflux molecules. The drug transport ...
a
Inhibitors affect the molecular pathway, and thus may affect substrate.
b
Clinically important genetics variants described.
A listing of CYP substrates, inhibitors, and inducers is...
... prevention and
treatment of eclamptic seizures. Two large randomized clinical trials have
demonstrated the superiority of magnesium sulfate over phenytoin and diazepam,
and a recent large randomized ... hypertension is associated with
intrauterine growth restriction and increased perinatal mortality. Pregnant women
with chronic hypertension are at increased risk for superimposed...
... observation.
Includes patients with exaggerated circadian rhythm.
Chapter 019. Fever of Unknown Origin
(Part 2)
Infections, especially extrapulmonary tuberculosis, remain the leading ... hyper-IgD syndrome,
tumor necrosis factor receptor associated periodic syndrome, familial cold
urticaria, and the Muckle-Wells syndrome), and Fabry disease.
A drug-related etiology must...
... worldwide
and for certain groups. The internist should promote preventive dental care and
hygiene as part of health maintenance. Special populations at high risk for dental
caries and periodontal ... dental care, and
language and cultural differences may create barriers that prevent some from
seeking preventive dental services.
Developmental and Systemic Disease Affecting t...
... causes of
morbidity and mortality are infection and complications of treatment with
glucocorticoids. Bad prognostic factors include advanced age, widespread
involvement, and the requirement ... directed against both Dsg3 and
Dsg1. Experimental studies have shown that autoantibodies from patients with PV
are pathogenic (i.e., responsible for blister formation) and that their tit...
... cm
3
) cells and kills the patient at a tumor cell burden of
about 10
12
(1 kg). Efforts to treat the tumor and reduce its size can result in an
increase in the growth fraction and an increase ...
minimally invasive, and if positive for cancer it may allow inception of systemic
treatment when metastatic disease is evident, or it can provide a basis for planning
a more meticulous...