Neurochemical Mechanisms in Disease P61 pps
Neurochemical Mechanisms in Disease P61 pps
... nitrated tau in pretangles, Brain Protein Oxidation in Alzheimer’s Disease 591 Table 1 Carbonylated and nitrated proteins in AD brain Protein Functions Carbonylated Proteins Nitrated Proteins References Energy-related ... and 3-nitrotyrosine (3-NT). Hence, measuring the levels of protein carbonyls and 3-NT reflects the level of protein oxidation in neurons. Increased oxidative stress...
Ngày tải lên: 07/07/2014, 09:20
Neurochemical Mechanisms in Disease P86 pps
... 299–301 in brain diseases, 307 domains, 298 in glial cells, 306 in Huntington’s disease (HD), 309–310 inhibitors, 297 in ischemic and traumatic brain injury, 307–308 in learning and memory, 305 in ... 364 Receptor-interacting kinase-1 (RIP1), 24 Reelin, 392 Rel family, 297 polypeptides, 301 Remyelination, in MS, 545 Renin-angiotensin system (RAS), 444 Retina, 250, 260 dopamine...
Ngày tải lên: 07/07/2014, 09:20
Neurochemical Mechanisms in Disease P1 ppsx
... material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Contents Mechanisms Versus Diagnoses 1 John P. Blass Molecular Mechanisms ... Neurodegenerative Disorders: Parkinson’s Disease and Alzheimer’s Disease 243 Ivan Bodis-Wollner and Herman Moreno NF-κB in Brain Diseases 293 Cheng-Xin Gong Trinucleotide-Expansion D...
Ngày tải lên: 07/07/2014, 09:20
Neurochemical Mechanisms in Disease P12 ppsx
... deficiencies, examines the role of vitamins in cellular function, and reviews current mechanisms involved in the pathogenesis of brain dysfunction in vitamin deficiencies. 2Thiamine(VitaminB 1 ) Thiamine is ... locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease- containing interval. Am J Hum Genet 74:11–19 Zuscik MJ, Sands S, Ross...
Ngày tải lên: 07/07/2014, 09:20
Neurochemical Mechanisms in Disease P13 pps
... resulting in increased prolactin release. Physiological levels of prolactin result in the initiation of lactation in females. Dopamine has an inhibitory effect resulting in decreased prolactin release. ... activity seen in pyridoxine-deficient rats. 4 Cobalamin (Vitamin B 12 ) Vitamin B 12 or cobalamin is present in meat and dairy products. Following ingestion, it is transformed in...
Ngày tải lên: 07/07/2014, 09:20
Neurochemical Mechanisms in Disease P19 pps
... human brain. (c) Location of dopaminergic neurons and their projections in the human brain Monoamine Transporter Pathologies 173 of terminating monoaminergic neurotransmitter signaling in the central ... disorder PD Parkinson’s disease PKC Protein kinase C β-PMA Phorbol 12-myristate13-acetate PP2A Protein phosphatase 2A SERT Serotonin transporter SNP Single nucleotide polymorphism SPECT...
Ngày tải lên: 07/07/2014, 09:20
Neurochemical Mechanisms in Disease P38 ppsx
... In normal brain tissue caspase-1 is activated within molecular platforms called in ammasomes. Key proteins of in ammasomes are proteins containing caspase recruitment domains (CARDS), or pyrin ... producing proinflammatory cytokines. These cytokines then enter the brain by volume diffusion. Third, the overflow of cytokines in the systemic circulation can gain entry to the brain via cytoki...
Ngày tải lên: 07/07/2014, 09:20
Neurochemical Mechanisms in Disease P44 pps
... cen- tral cholinergic components may be involved in the antinociception. For example, cholinergic stimulation of lateral hypothalamus increases the pain threshold by acti- vating the descending inhibitory ... shown that painful stimuli increase ACh level in the spinal cord releasing from the cholinergic interneurons in the SDH, and these neurons are activated by the inhibitory descendin...
Ngày tải lên: 07/07/2014, 09:20
Neurochemical Mechanisms in Disease P49 pps
... administration, the results are inconsistent. Thus, NAGly produces analge- sia administered in acute pain models including the HP and formalin tests and has anti -in ammatory activity (Burstein ... the chemokine fractalkine) mRNA, but not in the levels of fractalkine mRNA, in lumbar DRG significantly increase in neuropathic pain models (Holmes et al., 2008). IT or intra-PAG administrat...
Ngày tải lên: 07/07/2014, 09:20
Neurochemical Mechanisms in Disease P52 ppsx
... JM, Wang R (2008) In vivo characterization of the effects of human hemokinin-1 and human hemokinin-1(4–11), mammalian tachykinin peptides, on the modulation of pain in mice. Brain Behav Immun 22:850–860 Fu ... acid inhibits synaptic and acidic amino acid-induced responses in the rat hippocampus and spinal cord. Brain Res 273: 170–174 Gao L, Yu LC (2004) Involvement of opioid receptors...
Ngày tải lên: 07/07/2014, 09:20