Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P4 potx
Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P4 potx
... of alcohol, diabetes, and
viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the U.S. Cancer
101:1009–1017
1 Epidemiology and Pathogenesis of Hepatocellular Carcinoma ... genes and miRNAs in biological pathways. Furthermore, signif-
icant and complex cross talks among the different pathways exist and are involved
in different aspects of HCC develop...
Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P2 potx
... Pritesh Mutha, and Sanjay Gupta
21 Cytotoxic Chemotherapy and Endocrine Therapy
for Hepatocellular Carcinoma 337
Daniel Palmer and Philip J. Johnson
22 Targeted Therapies for Hepatocellular Carcinoma ... Albany, and Ghassan K. Abou-Alfa
23 The Future: Combination Systemic Therapy
for Hepatocellular Carcinoma 369
Ahmed O. Kaseb and Melanie B. Thomas
24 Follow-Up and Sal...
Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P10 potx
... system (and related JIS score) may, however,
have particular advantages in patients with early HCC. As the therapeutic modalities
available for HCC and the indications for aggressive therapy expand, ... multimodal-
ity therapy can be expected to challenge our understanding of prognostic factors
in HCC.
References
1. Okuda K, Ohtsuki T, Obata H et al (1985) Natural history of hepatocel...
Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P14 potx
... (TLV) is defined as
the standardized FLR (sFLR) and it provides the percent of TLV remaining after resection
Preoperative Therapy
Transarterial Chemoembolization (TACE) and Portal Vein Embolization
(PVE)
In ... mechanism of intrahepatic recurrence, and later
to extrahepatic organs such as the lungs, bone, and adrenal glands. These two forms
of spread, vascular invasion and intrahep...
Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P16 potx
... veins as
landmarks to reduce the risk of major morbidity and mortality.
Definition of the tumor–vessels relationship is relevant for planning the type of
resection, and based on that, specific and original ... vein could be thicker
and not immediately differentiable from a peripheral portal branch. Following the
portal pedicles at the sectional, segmental, and subsegmental levels and...
Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P20 potx
... remnant, and recognition of the physiologic effect
of the type of hepatic and extrahepatic procedure planned, permits the appropriate
selection of patients for PVE. The FLR should be measured and standardized ... function and posthepatectomy course and the utility of PVE in patients
with HCC. Palavecino and colleagues [112] evaluated 54 patients that underwent
major hepatic resect...
Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P24 potx
... open resection and the need for blood transfusion were 9.2 and 9.8%, respec-
tively. There were 2 postoperative deaths and the morbidity was detailed as liver
specific in 11.6% and nonspecific ... injection therapy for
hepatocellular carcinoma: results in 146 patients. AJR Am J Roentgenol 160(5):1023–1028
6. Matsukawa T, Yamashita Y, Arakawa A, et al (1997) Percutaneous microwave...
Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P28 potx
... Resection for Hepatocellular Carcinoma 255
perform these resections. More importantly, such surgeons should understand the
risks, benefits and limitations of these highly aggressive procedures and that ... (2008) Contrast-enhanced ultrasonography and spiral com-
puted tomography in the detection and characterization of portal vein thrombosis complicating
hepatocellular carcinoma. E...
Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P33 potx
... Beads 305
Fig. 19.4 Response. (a) Pre Drug Eluting Bead Therapy; (b) 6 weeks post therapy; (c) 6 months
post therapy; (d) 12 months post therapy
The European Association for the Study of the Liver ... of DEB-TACE and higher levels of chemotherapy.
Patients who did not respond adequately to initial therapy and who did not have
significant toxicity were candidates for additional treat...
Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary P37 potx
... Treatment
of hepatocellular carcinoma with combined suppression and inhibition of sex hormones: a
randomized, controlled trial. Hepatology 21:1535–1542
21 Cytotoxic Chemotherapy and Endocrine Therapy ... such as lamivudine [78]. A non-
randomized comparison of HBV-positive patients receiving chemotherapy reported
21 Cytotoxic Chemotherapy and Endocrine Therapy for Hepatocellular...
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