Chapter 114 Molecular Mechanisms of Microbial Pathogenesis (Part 2) potx
Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 2) potx
... matrix
proteins
Chapter 114. Molecular Mechanisms
of Microbial Pathogenesis
(Part 2)
Table 114- 1 Examples of Microbial Ligand-Receptor Interactions
Microorganism
Type of Microbial
Ligand ... cell–specific C-type lectin.
antigens
Bacterial
Pathogens
Neisseria spp. Pili
Membrane cofactor
protein (CD46)
Pseudomonas
aeruginosa
Pili and flagell...
Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 1) potx
... Mechanisms
of Microbial Pathogenesis
(Part 1)
Harrison's Internal Medicine > Chapter 114. Molecular Mechanisms of
Microbial Pathogenesis
Molecular Mechanisms of Microbial Pathogenesis: ... decades, molecular studies of the pathogenesis of
microorganisms have yielded an explosion of information about the various
microbial and host molec...
Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 4) potx
... mediate colonization of
epithelial surfaces, particularly adherence to structures like fibronectin, laminin,
Chapter 114. Molecular Mechanisms
of Microbial Pathogenesis
(Part 4)
Flagella ... Binding of the highly conserved Staphylococcus aureus
surface protein clumping factor A (ClfA) to fibrinogen has been implicated in
many aspects of pathogenesis. The conserve...
Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 3) doc
... detail of the bacterial
surface structures. (Images courtesy of Dr. Martin Lee and Dr. Milan Bajmoczi,
Harvard Medical School.)
Chapter 114. Molecular Mechanisms
of Microbial Pathogenesis
(Part ... micrographic
images of fixed cells of Pseudomonas aeruginosa. Flagella (A) and pili (B)
projecting out from the bacterial poles can be seen. C and D
. Atomic force...
Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 5) ppt
... Chapter 114. Molecular Mechanisms
of Microbial Pathogenesis
(Part 5)
Numerous virus–target cell interactions have been described, ... several examples of microbial biofilm growth associated
with human disease. Many other pathogens can form biofilms during in vitro
growth, and it is increasingly accepted that this mode of growth ... grow. The growth of
viral path...
Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 6) docx
...
Chapter 114. Molecular Mechanisms
of Microbial Pathogenesis
(Part 6)
Encounters with Epithelial Cells
Over the past decade, ...
epithelial cells (Fig. 114- 2); the bacteria often use specialized surface structures
that bind to receptors, with consequent internalization. However, the exact role
and the importance of this process ... ingestion and killing by professi...
Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 7) ppsx
... (LBP), transfers LPS to
Chapter 114. Molecular Mechanisms
of Microbial Pathogenesis
(Part 7)
Encounters with Phagocytes
Phagocytosis and Inflammation
Phagocytosis of microbes is a major ... to our understanding of molecular mechanisms
of microbial pathogenesis (Fig. 114- 3). One of the best-studied systems involves
the interaction of LPS from gram-neg...
Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 8) pdf
... Chapter 114. Molecular Mechanisms
of Microbial Pathogenesis
(Part 8)
GPI-anchored receptors do not have intracellular signaling ... through a series of signal-
transducing molecules (Fig. 114- 3) that lead to nuclear translocation of the
transcription factor nuclear factor κB (NF-κB), a master-switch for production of
important ... the microbe.
This interaction i...
Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 9) pot
... of diseases like toxic shock syndrome and scarlet fever. A number of
Chapter 114. Molecular Mechanisms
of Microbial Pathogenesis
(Part 9)
Fungal pathogens almost always take advantage of ... toxin production
is one of the best-characterized molecular mechanisms of pathogenesis, while host
factors such as IL-1, TNF-α, kinins, inflammatory proteins, products...
Chapter 114. Molecular Mechanisms of Microbial Pathogenesis (Part 10) pps
... leads to fever, muscle proteolysis, and other effects, as noted
Chapter 114. Molecular Mechanisms
of Microbial Pathogenesis
(Part 10)
Invasion
Many diseases are caused primarily by pathogens ... importance of this structure in pathogenesis.
Host Response
The inflammatory response of the host is critical for interruption and
resolution of the infectious process b...
Từ khóa: