Chapter 107 Transfusion Biology and Therapy (Part 3) pptx

... anti-Jk a . Pretransfusion Testing Pretransfusion testing of a potential recipient consists of the "type and screen." The "forward type" determines the ABO and Rh phenotype ... product CCI ≥10 x 10 9 /L within 1 h and ≥7.5 x 10 9 /L within 24 h posttransfusion FFP 200–250 Plasma proteins— coagulation factors, proteins C and S, antithrombin Incre...

Ngày tải lên: 07/07/2014, 04:20

... this binding. Chapter 107. Transfusion Biology and Therapy (Part 1) Harrison's Internal Medicine > Chapter 107. Transfusion Biology and Therapy Blood Group Antigens and Antibodies ... phenotype) as well as to both A and B antigens and are therefore compatible only with other hh donors. In most people, A and B antigens are secreted by the cells...

Ngày tải lên: 07/07/2014, 04:20

... Donath-Landsteiner antibodies. The P antigen is the cellular receptor of parvovirus B19 and also may be a receptor for Escherichia coli binding to urothelial cells. Chapter 107. Transfusion Biology ... cells. Chapter 107. Transfusion Biology and Therapy (Part 2) Rh System The Rh system is the second most important blood group system in pretransfusion testin...

Ngày tải lên: 07/07/2014, 04:20

... 100 g/L are sufficient to keep oxygen supply from being critically low. Chapter 107. Transfusion Biology and Therapy (Part 4) Apheresis technology is used for the collection of multiple ... platelet-specific antigens and have little or no increase in their posttransfusion platelet counts. Patients who may require multiple transfusions are best served by receiving SDAP...

Ngày tải lên: 07/07/2014, 04:20

... adverse reaction is suspected, the transfusion should be stopped and reported to the blood bank for investigation. Chapter 107. Transfusion Biology and Therapy (Part 5) Fresh-Frozen Plasma ... transfusion therapy. Infections, like any adverse transfusion reaction, must be brought to the attention of the blood bank for appropriate studies (Table 107- 3). Table 1...

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... characterized by chills and rigors and a ≥1°C rise in temperature. Chapter 107. Transfusion Biology and Therapy (Part 6) Immune-Mediated Reactions Acute Hemolytic Transfusion Reactions Immune-mediated ... No specific therapy is usually required, although additional RBC transfusions may be necessary. Delayed serologic transfusion reactions are similar to DHTR,...

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... Chapter 107. Transfusion Biology and Therapy (Part 7) Anaphylactic Reaction This severe reaction presents after transfusion of only a few milliliters of the blood component. Symptoms and ... coughing, nausea and vomiting, hypotension, bronchospasm, loss of consciousness, respiratory arrest, and shock. Treatment includes stopping the transfusion, maintaining vas...

Ngày tải lên: 07/07/2014, 04:20

... been obtained and are unlikely to be obtained as the blood supply becomes universally leukocyte- depleted. Infectious Complications Chapter 107. Transfusion Biology and Therapy (Part 8) Nonimmunologic ... Blood components are excellent volume expanders, and transfusion may quickly lead to volume overload. Monitoring the rate and volume of the transfusion and...

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... Chapter 107. Transfusion Biology and Therapy (Part 9) Other Hepatitis Viruses Hepatitis A virus is rarely transmitted by transfusion; infection is typically asymptomatic and does ... septic shock and DIC. These reactions may occur abruptly, within minutes of initiating the transfusion, or after several hours. The onset of symptoms and signs is often sudden and...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 107. Transfusion Biology and Therapy (Part 10) Alternatives to Transfusion Alternatives to allogeneic blood transfusions that avoid homologous ... (eds): Blood Banking and Transfusion Medicine: Basic Principles and Practices, 2d ed. Philadelphia, Churchill Livingstone, 2006 Kitchen AD, Chiodini PL: Malaria and blood transfusion. Vox Sang ... Transfusi...

Ngày tải lên: 07/07/2014, 04:20