Chapter 105 Malignancies of Lymphoid Cells (Part 4) pptx
Chapter 005. Principles of Clinical Pharmacology (Part 4) ppsx
... orally
Chapter 005. Principles of Clinical
Pharmacology
(Part 4)
Clinical Implications of Drug Distribution
Digoxin accesses its cardiac site of action slowly, over a distribution phase
of ... volume of distribution of lidocaine is reduced. Therefore, lower-than-
normal loading regimens are required to achieve equivalent plasma drug
concentrations and to avoid toxici...
Chapter 019. Fever of Unknown Origin (Part 4) ppt
...
Figure 19-1
Chapter 019. Fever of Unknown Origin
(Part 4)
Specialized Diagnostic Studies
Classic FUO
A stepwise flow chart depicting the diagnostic workup and therapeutic
management of FUO ... parasitic genera and species. The eventual
clinical validation of such microarrays will further diminish rates of undiagnosed
FUO of infectious etiology.
tissue removed dur...
Chapter 029. Disorders of the Eye (Part 4) potx
... color vision frequently result from disease of the macula or
optic nerve.
For example, patients with a history of optic neuritis often complain of
color desaturation long after their visual ... automated printout of light thresholds, these static
perimeters provide a sensitive means of detecting scotomas in the visual field.
They are exceedingly useful for serial assessment of...
Chapter 062. Principles of Human Genetics (Part 4) ppsx
... (or linked
genes) with the presence of a disease or genetic trait (see below).
Chapter 062. Principles of
Human Genetics
(Part 4)
Figure 62-2
Flow of genetic information. Multiple extracellular ... among others. Many of these disorders
strongly predispose to neoplasia because of the rapid acquisition of additional
mutations (Chap. 79). After completion of DNA s...
Chapter 005. Principles of Clinical Pharmacology (Part 7) pptx
... Chapter 005. Principles of Clinical
Pharmacology
(Part 7)
Renal Disease
Renal excretion of parent drug and metabolites is generally accomplished ... of lidocaine is
reduced by about 50% in heart failure, and therapeutic plasma levels are achieved
at infusion rates of 50% or less than those usually required. The volume of
distribution of ... linked to the occurrence...
Chapter 024. Gait and Balance Disorders (Part 4) pptx
... observation provides an immediate sense of the patient's degree of
disability. Characteristic patterns of abnormality are sometimes observed, though
failing gaits often look fundamentally similar. ... to mean the ability of the
organism to control the center of mass with respect to gravity and the support
surface. In reality, no one is aware of what or where the center o...
Chapter 019. Fever of Unknown Origin (Part 2) pptx
... actual fever observed during 2–3 weeks of inpatient observation.
Includes patients with exaggerated circadian rhythm.
Chapter 019. Fever of Unknown Origin
(Part 2)
Infections, especially ... most frequent cause of FUO,
giant-cell arteritis being the leading etiologic entity in this category. In patients
>50 years of age, this disease accounts for 15–20% of FUO cases...
Chapter 029. Disorders of the Eye (Part 23) pptx
... examination
of the eyes. Observation of nystagmoid movements of the optic disc on
ophthalmoscopy is a sensitive way to detect subtle nystagmus.
Gaze-Evoked Nystagmus
This is the most common form of ... 295:1077, 2002
Trobe JD: The Neurology of Vision
, Univ Michigan Med School
(Contemporary Neurology Series 60), 2001
Chapter 029. Disorders of the Eye
(Part 23)
Pari...
Chapter 029. Disorders of the Eye (Part 3) pptx
... denervation of the iris sphincter the pupil does not respond well to
light, but the response to near is often relatively intact. When the near stimulus is
Chapter 029. Disorders of the Eye
(Part ... varies.
Anisocoria that increases in dim light indicates a sympathetic paresis of the iris
dilator muscle.
The triad of miosis with ipsilateral ptosis and anhidrosis constitutes...
Chapter 062. Principles of Human Genetics (Part 12) pptx
... Chapter 062. Principles of
Human Genetics
(Part 12)
The Genetic Map
Given the size and complexity of the human genome, initial efforts aimed
at ... the identification of disease-causing genes by
positional cloning.
Recent insights into the structure of the normal human genome show that
certain blocks of DNA sequences, often containing numerous ...
corresponds to ~1 M...
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