Chapter 063. Chromosome Disorders (Part 2) potx
... Chapter 063. Chromosome Disorders (Part 2) Molecular Cytogenetics The introduction of FISH methodologies in the ... chromosome-specific paints (chromosome libraries), repetitive probes, and single- copy probes (Fig. 63 -2). Chromosome libraries hybridize to sequences that span the entirety of the chromosome from which
Ngày tải lên: 07/07/2014, 01:20
Chapter 079. Cancer Genetics (Part 2) potx
... Chapter 079. Cancer Genetics (Part 2) General Classes of Cancer Genes There are two major classes of cancer genes. The first class comprises genes ... formulated the two-hit hypothesis, which in its modern version states that both copies of a tumor-suppressor gene must be inactivated in cancer. The second class of cancer genes, the caretakers, ... first hypothesized b...
Ngày tải lên: 07/07/2014, 01:20
... messengers of threats to tissue injury but also play an active role in Chapter 012. Pain: Pathophysiology and Management (Part 2) Sensitization When intense, repeated, or prolonged stimuli are ... activated (Fig. 12 -2). An example is substance P, an 11- amino-acid peptide. Substance P is released from primary afferent nociceptors and has multiple biologic activities. It is a po...
Ngày tải lên: 06/07/2014, 08:20
... Chapter 018. Fever and Rash (Part 2) Centrally Distributed Maculopapular Eruptions Centrally distributed rashes, ... confused with Fordyce's spots (ectopic sebaceous glands), which have no erythematous halos and are found in the mouth of healthy individuals. Koplik's spots may briefly overlap with ... begins as discrete erythematous lesions, which become confluent as...
Ngày tải lên: 06/07/2014, 12:20
Chapter 020. Hypothermia and Frostbite (Part 2) pot
... initial stimulation by hypothermia, there is progressive depression of all organ systems. The timing of the appearance of these clinical manifestations varies widely (Table 20 -2). Without knowing ... patient with mild hypothermia should raise suspicion of an overdose or CNS dysfunction due to infection or trauma. Table 20-2 Physiologic Changes Associated with Accidental Hypothermia nt...
Ngày tải lên: 06/07/2014, 12:21
Chapter 021. Syncope (Part 2) potx
... syncope can be associated with prolonged asystole and hypotension, resulting in hypoxic-ischemic injury. Chapter 021. Syncope (Part 2) Disorders of Vascular Tone or Blood Volume Disorders
Ngày tải lên: 06/07/2014, 12:21
Chapter 023. Weakness and Paralysis (Part 2) pot
... motor neurons have their cell bodies in layer V of the primary motor cortex Chapter 023. Weakness and Paralysis (Part 2) Pathogenesis Upper Motor Neuron Weakness This pattern of weakness
Ngày tải lên: 06/07/2014, 13:20
Chapter 026. Confusion and Delirium (Part 2) potx
... Chapter 026. Confusion and Delirium (Part 2) Epidemiology Delirium is a common disease, but its reported incidence
Ngày tải lên: 06/07/2014, 13:20
Chapter 032. Oral Manifestations of Disease (Part 2) potx
... Developmental and Systemic Disease Affecting the Teeth and Periodontium Chapter 032. Oral Manifestations of Disease (Part 2) Periodontal Disease Periodontal disease accounts for more tooth
Ngày tải lên: 06/07/2014, 15:21
Chapter 033. Dyspnea and Pulmonary Edema (Part 2) potx
... may reduce breathing discomfort, in part, by altering this dimension. Chapter 033. Dyspnea and Pulmonary Edema (Part 2) Integration: Efferent-Reafferent Mismatch A discrepancy or mismatch
Ngày tải lên: 06/07/2014, 15:21