Chapter 086 Breast Cancer (Part 1) potx

... full-term pregnancy. Chapter 086. Breast Cancer (Part 1) Harrison's Internal Medicine > Chapter 86. Breast Cancer Breast Cancer: Introduction Breast cancer is a malignant proliferation ... these genes play in inherited forms of breast cancer may be their role in sporadic breast cancer. The p53 mutation is present in nearly 40% of human breast c...

Ngày tải lên: 07/07/2014, 02:20

... Chapter 086. Breast Cancer (Part 4) If a nonpalpable mammographic lesion has a low index of suspicion, mammographic ... f/u, follow-up. Breast Masses in the Pregnant or Lactating Woman continue to believe that screening conveys substantial benefit. Furthermore, the profound drop in breast cancer mortality seen ... diagnosis, and women who have had a biopsy with beni...

Ngày tải lên: 07/07/2014, 02:20

... circumstances they may provoke a biopsy. Chapter 086. Breast Cancer (Part 3) The Palpable Breast Mass Women should be strongly encouraged to examine their breasts monthly. A potentially flawed ... during the follicular phase of the menstrual cycle. Days 5–7 of the cycle are the best time for breast examination. A dominant mass in a postmenopausal woman or a dominant mas...

Ngày tải lên: 07/07/2014, 02:20

... sentinal lymph node dissection but not clinically apparent Chapter 086. Breast Cancer (Part 5) Staging Correct staging of breast cancer patients is of extraordinary importance. Not only ... Used with permission of the American Joint Committee on Cancer (AJCC), Chicago, Illinois. The original sour ce for this material is the AJCC Cancer Staging Manual, Sixth Edition (...

Ngày tải lên: 07/07/2014, 02:20

... appropriate systemic regimen. Prognostic Variables Chapter 086. Breast Cancer (Part 6) Breast Cancer: Treatment Primary Breast Cancer Breast- conserving treatments, consisting of the removal ... therapy after local management of breast cancer substantially improves survival. More than one-third of the women who would otherwise die of metastatic breast cancer...

Ngày tải lên: 07/07/2014, 02:20

... IIIA 47 IIIB 44 IV 14 Source: Modified from data of the National Cancer Institute— Surveillance, Epidemiology, and End Results (SEER). Estrogen and progesterone

Ngày tải lên: 07/07/2014, 02:20

... although small advantages for doxorubicin-containing regimens are usually seen. Chapter 086. Breast Cancer (Part 8) Table 86-3 Suggested Approaches to Adjuvant Therapy Age Group Lymp h

Ngày tải lên: 07/07/2014, 02:20

... liver) metastases each account for approximately one-third of sites of initial Chapter 086. Breast Cancer (Part 9) One approach—so-called neoadjuvant chemotherapy—involves the administration ... misdiagnosed and treated as though they had metastatic breast cancer or even second malignancies such as multiple myeloma thought to be recurrent breast cancer. This is a cata...

Ngày tải lên: 07/07/2014, 02:20

... Chapter 086. Breast Cancer (Part 10) Endocrine Therapy Normal breast tissue is estrogen-dependent. Both primary and metastatic breast cancer may retain this phenotype. ... metastatic breast cancer may retain this phenotype. The best means of ascertaining whether a breast cancer is hormone-dependent is through analysis of estrogen and progesterone receptor levels...

Ngày tải lên: 07/07/2014, 02:20

... disease-free survival in about 30–50% of patients. Breast Cancer Prevention Women who have one breast cancer are at risk of developing a contralateral breast cancer at a rate of approximately 0.5% per ... disease. Stage III Breast Cancer Between 10 and 25% of patients present with so-called locally advanced, or stage III, breast cancer at diagnosis. Many of these c...

Ngày tải lên: 07/07/2014, 02:20