Chapter 085 Neoplasms of the Lung (Part 16) doc

... months; <5% of patients survive 2 Chapter 085. Neoplasms of the Lung (Part 16) Chemotherapy Chemotherapy palliates symptoms, improves the quality of life, and improves survival in newly ... is an oral inhibitor of the EGFR kinase that is used in second- and third-line therapy of NSCLC. Clinical responses have been seen in a large fraction of the small...

Ngày tải lên: 07/07/2014, 01:20

... one-third have Chapter 085. Neoplasms of the Lung (Part 6) Diagnosis and Staging Screening Most patients with lung cancer present with advanced disease, raising the question of whether screening ... (whether the tumor can be entirely removed by a standard surgical procedure such as a lobectomy or pneumonectomy), which depends on the anatomic stage of the t...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 085. Neoplasms of the Lung (Part 12) Non-Small Cell Lung Cancer NSCLC Stages I and II Surgery In patients with NSCLC ... doses of 60–64 Gy, while palliative thoracic radiation (see below) involves delivery of 30–45 Gy. The major dose-limiting concern is the amount of lung parenchyma and other organs in the thorax ... sometimes progress to pulmona...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 085. Neoplasms of the Lung (Part 17) Chemotherapy The chemotherapy combination most widely used for SCLC is etoposide plus ... signs of bleeding or infection, and, as required, use of hematopoietins) and adjustment of chemotherapy doses on the basis of nadir granulocyte counts are essential. The prognosis of patients ... Radiation Therapy for Pallia...

Ngày tải lên: 07/07/2014, 01:20

... 60,514 cases of invasive lung cancer involving all races and both sexes obtained from the data for 1983–1987 of the S urveillance, Epidemiology, and End Results (SEER) Program of the National ... represents one lung cancer case for every 3 million cigarettes smoked. Thus, primary carcinoma of the lung is a major health problem with a generally grim prognosis. Pathol...

Ngày tải lên: 07/07/2014, 01:20

... smoking-related, further increases the risk of developing lung cancer. The lung cancer death rate is related to the total amount (often expressed in "cigarette pack-years") of cigarettes ... are clinically localized at the time of presentation may be cured with either surgery or radiotherapy. The beneficial role of chemotherapy in NSCLC is in palliation of...

Ngày tải lên: 07/07/2014, 01:20

... cancers other than lung cancer, nor in lung cancers that have KRAS mutations. These EGFR mutations, often associated with amplification of the EGFR gene, usually confer sensitivity of these lung ... Chapter 085. Neoplasms of the Lung (Part 4) Inherited Predisposition to Lung Cancer While an inherited predisposition to develop lung cancer is not common, s...

Ngày tải lên: 07/07/2014, 01:20

... uncommon (1%), as are the renal manifestations of nephrotic syndrome or glomerulonephritis (≤1%). Chapter 085. Neoplasms of the Lung (Part 5) Clinical Manifestations Lung cancer gives rise ... inappropriate palliative rather than curative treatment. Often the paraneoplastic syndrome may be relieved with successful treatment of the tumor. In some cases, the...

Ngày tải lên: 07/07/2014, 01:20

... <2 cm distal to carina but without involvement of carina; or associated atelectasis or obstructive pneumonitis of entire lung for Staging of Lung Cancer. Chest 111:1710, 1997; with permission. ... metastatic pulmonary tumor nodule(s) in the ipsilateral nonprimary tumor lobe(s) of the lung are classified as M1. Source: Adapted from CF Mountain. Revisions in the Int...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 085. Neoplasms of the Lung (Part 8) Small Cell Lung Cancer A simple two-stage system is used. In this system, limited-stage disease (seen in about 30% of all patients ... tuberculosis Chest x-ray CT scan of chest and abdomen CT or MRI scan of brain and radionuc lide scan of bone if any finding suggests the presence of tumor metastasis in these or...

Ngày tải lên: 07/07/2014, 01:20