Chapter 083 Cancer of the Skin (Part 4) pot

... from RJ Friedman et al: CA— A Cancer J Clinicians 33(3):130, 1985. Chapter 083. Cancer of the Skin (Part 4) Management The entire cutaneous surface, including the scalp and mucous membranes, ... areas; the back is the most common site, but dysplastic nevi may also be seen on the scalp, breast s, and buttocks Generally on the sun- exposed surfaces of...

Ngày tải lên: 07/07/2014, 01:20

... thick) reported that the narrower margin resulted in higher rates of local recurrence but no difference in rates of nodal or distant metastases, Chapter 083. Cancer of the Skin (Part 6) Biopsy ... excision of the lesion with a margin of normal skin is necessary to remove all malignant cells and minimize possible local recurrence. The appropriate width of...

Ngày tải lên: 07/07/2014, 01:20

... on the palms and soles. Lateral Chapter 083. Cancer of the Skin (Part 1) Harrison's Internal Medicine > Chapter 83. Cancer of the Skin Melanoma Pigmented lesions are among the ... Dark-skinned populations (such as those of India and Puerto Rico), blacks, and East Asians have rates 10–20 times lower than lighter- skinned whites. In keeping with the...

Ngày tải lên: 07/07/2014, 01:20

... Shades of brown mixed with bluis h red (violaceous), bluish black, reddish brown, and often whitish pink, and the border of lesion is at least in part a During much of thi s time, the ... spreading melanoma is the most frequent variant observed in the white population. Melanomas arising in dysplastic nevi (see below) are usually of this type. The back is the m...

Ngày tải lên: 07/07/2014, 01:20

... color from flesh to tan, to dark brown. Chapter 083. Cancer of the Skin (Part 5) A lifetime risk of melanoma development of 6% has been estimated. The risk is greatest before age 5 and next ... Early detection of melanoma is difficult in these lesions because of the deep dermal or subcutaneous origin of primary melanoma and because of the large and varie...

Ngày tải lên: 07/07/2014, 01:20

... telangiectatic tumor border. Chapter 083. Cancer of the Skin (Part 7) Treatment of Metastatic Disease Melanoma can metastasize to any internal organ, the brain being a particularly common ... skin such as the head, neck, hands, and arms are other typical sites of involvement. C. Actinic keratoses consists of hyperkeratotic erythematous papules and patches...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 083. Cancer of the Skin (Part 9) Squamous Cell Carcinoma The natural history of SCC depends on both tumor and host characteristics. Tumors arising on actinically damaged skin ... decrease the rate of NMSC in xeroderma pigmentosum. Squamous Cell Carcinoma The therapy of cutaneous SCC should be based on an analysis of risk factors influencing the b...

Ngày tải lên: 07/07/2014, 01:20

... Jr et al: The histogenesis and biologic behavior of primary human malignant melanoma of the skin. Cancer Res 29:705, 1969 [PMID: 5773814] Friedman RI et al (eds): Cancer of the Skin. Philadelphia, ... 258:3146, 1987 [PMID: 3312689] Chapter 083. Cancer of the Skin (Part 10) Other Nonmelanoma Cutaneous Malignancies Neoplasms of cutaneous adnexa and sar...

Ngày tải lên: 07/07/2014, 01:20

... be impaired by damage to the visual system anywhere from the eyes to the occipital lobes. One can localize the site of the lesion with considerable accuracy by mapping the visual field deficit ... frequently result from disease of the macula or optic nerve. For example, patients with a history of optic neuritis often complain of color desaturation long after their v...

Ngày tải lên: 06/07/2014, 15:21

... other than lung cancer, nor in lung cancers that have KRAS mutations. These EGFR mutations, often associated with amplification of the EGFR gene, usually confer sensitivity of these lung cancers ... cases the development of EGFR TKI resistance is associated with the development of another mutation in the EGFR gene (T790M mutation), or amplification of the c-met oncoge...

Ngày tải lên: 07/07/2014, 01:20