Chapter 081 Principles of Cancer Treatment (Part 18) pps
Chapter 081. Principles of Cancer Treatment (Part 18) pps
... spectrum of activity to imatinib, but with increased
potency and perhaps better tolerance by certain patients. Dasatinib, another
Chapter 081. Principles of
Cancer Treatment
(Part 18)
Site of ... superior to interferon plus
chemotherapy in the initial treatment of the chronic phase of this disorder. It has
lesser activity in the blast phase of CML, where the...
Chapter 081. Principles of Cancer Treatment (Part 2) ppsx
... those with pancolonic involvement with ulcerative colitis), the presence of
Chapter 081. Principles of
Cancer Treatment
(Part 2)
Figure 81-1
...
Principles of Cancer Surgery
Surgery is used in cancer prevention, diagnosis, staging, treatment (for both
localized and metastatic disease), palliation, and rehabilitation.
Prophylaxis
Cancer ... incisional b...
Chapter 081. Principles of Cancer Treatment (Part 3) pps
... information for treatment planning and may determine the extent and nature of
primary cancer treatment.
Treatment
Surgery is the most effective means of treating cancer. Today about 40% of
cancer ... resection of certain tumors that would otherwise not be
possible.
Chapter 081. Principles of
Cancer Treatment
(Part 3)
Staging
As noted in Chap. 77, an i...
Chapter 081. Principles of Cancer Treatment (Part 6) ppsx
... dose of therapeutic radiation exists below which the
incidence of second cancers is decreased. High rates of second tumors occur in
people who receive as little as 1000 cGy.
Chapter 081. Principles ... breast cancer, Hodgkin's disease, head and neck cancer,
prostate cancer, and gynecologic cancers. Radiation therapy can also palliate
disease symptoms in a variety of...
Chapter 081. Principles of Cancer Treatment (Part 12) ppsx
... Chapter 081. Principles of
Cancer Treatment
(Part 12)
Direct DNA-Interactive Agents
DNA replication occurs during the synthesis or S-phase of the cell cycle,
with ... cause profound myelosuppression,
alopecia, and pulmonary toxicity but is relatively "lymphocyte sparing." Its routine
case. Thiotepa can be used for intrathecal treatment of neoplastic ... n...
Chapter 081. Principles of Cancer Treatment (Part 14) pps
... action of a DNA
damage checkpoint. Prominent clinical effects include myelosuppression, nausea,
Chapter 081. Principles of
Cancer Treatment
(Part 14)
Mitomycin C undergoes reduction of its ... arisen shortly after exposure of patients to mitoxantrone, particularly
in the adjuvant treatment of breast cancer. While chemotherapy-associated
leukemia is generally o...
Chapter 081. Principles of Cancer Treatment (Part 15) ppsx
... motile and secretory processes occur. Microtubules are composed of
repeating noncovalent multimers of a heterodimer of α and subunits of the protein
tubulin. Vincristine binds to the tubulin dimer ... refractory cancers.
Intravenous administration of 5FU leads to bone marrow suppression after short
infusions but to stomatitis after prolonged infusions. Leucovorin augments the
a...
Chapter 081. Principles of Cancer Treatment (Part 24) ppsx
... targets of T cell killing greatly expanded the possibilities for
Chapter 081. Principles of
Cancer Treatment
(Part 24)
Immune Mediators of Antitumor Effects
The very existence of a cancer ... is testimony to the failure of the
immune system to deal effectively with the cancer. Tumors have a variety of
means of avoiding the immune system: (1) they are often...
Chapter 081. Principles of Cancer Treatment (Part 1) docx
... benefit. One of the challenges of cancer
treatment is to use the various treatment modalities alone and together in a fashion
that maximizes the chances for patient benefit.
Cancer treatments ... attention to minimizing the toxicity of
potentially toxic treatments becomes a significant goal. Irrespective of the clinical
scenario, the guiding principle of cancer treatme...
Chapter 081. Principles of Cancer Treatment (Part 4) pdf
... Chapter 081. Principles of
Cancer Treatment
(Part 4)
Palliation
Surgery is employed in a number of ways for supportive care: insertion of
central venous catheters, control of pleural ... for recurrent pulmonary emboli, stabilization of cancer-
weakened weight-bearing bones, and control of hemorrhage, among others.
Surgical bypass of gastrointestinal, urinary...
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