... but the largest genes (Fig. 62-14). Figure 62-14 Chapter 062. Principles of Human Genetics (Part 29) Population Genetics In population genetics, the focus changes from alterations in an ... with p2 corresponding to the frequency of AA, 2pq to the frequency of Aa, and q2 to aa. When the frequency of an allele is known, the frequency of the genotype can be calculated. Alternatively, ... potential implications of positive results, including psychological distress and the possibility of discrimination. The patient or caretakers should be informed about the meaning of a negative result,...