Chapter 057 Photosensitivity and Other Reactions to Light (Part 7) docx
Chapter 057. Photosensitivity and Other Reactions to Light (Part 7) docx
... Fig. 57-1. Figure 57-1 Chapter 057. Photosensitivity and Other Reactions to Light (Part 7) Porphyria cutanea tarda is the most common type of human porphyria and is associated with decreased ... include an acute photosensitivity characterized by subjective burning and stinging of exposed skin that often An algorithm for the diagnosis of a patient with photosensitivity. Photoprotection ... protoporphyrin helps to differentiate lead poisoning and iron-deficiency anemia, in both of which elevated erythrocyte protoporphyrin levels occur in the absence of cutaneous photosensitivity and of elevated...
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Chapter 057. Photosensitivity and Other Reactions to Light (Part 1) pps
... penetrates to the dermis and is capable of altering structural and matrix proteins that contribute to photoaging of chronically sun-exposed skin, particularly in individuals of light complexion. ... between 290 and Photosensitivity occurs when a photon-absorbing chemical (chromophore) present in the skin absorbs incident energy, becomes excited, and transfers the absorbed energy to various ... wavelengths between 320 and 400 nm and is ~1000-fold less efficient in producing skin redness than is UV-B. The wavelengths between 400 and 700 nm are visible to the human eye. The photon energy in...
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Chapter 057. Photosensitivity and Other Reactions to Light (Part 2) pps
... extent in the Chapter 057. Photosensitivity and Other Reactions to Light (Part 2) Molecular Targets for UVR-Induced Skin Effects Epidermal DNA, predominantly in keratinocytes and in Langerhans ... released into the circulation from the bone marrow and the liver and are transported to the skin, where they absorb incident energy both in the Soret band, around 400 nm (short visible), and to a ... production and/ or release of vasoactive mediator(s), or cytokines, that diffuse to the dermal vasculature to evoke vasodilatation. The action spectrum for sunburn erythema includes the UV-B and UV-A....
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Chapter 057. Photosensitivity and Other Reactions to Light (Part 5) pps
... Chapter 057. Photosensitivity and Other Reactions to Light (Part 5) Polymorphous Light Eruption After sunburn, the most common type of photosensitivity disease is polymorphous light eruption ... exposure. Phototoxicity and Photoallergy These photosensitivity disorders are related to the topical or systemic administration of drugs and other chemicals. Both reactions require the absorption ... sunscreens and the induction of hardening by the cautious administration of artificial UV-B (broad-band or narrow-band) and/ or UV-A radiation for 2–3 weeks prior to initial sun exposure. Phototoxicity...
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Chapter 057. Photosensitivity and Other Reactions to Light (Part 6) ppsx
... persistent photosensitivity is known as chronic actinic dermatitis. These patients are typically elderly men with a long history of Chapter 057. Photosensitivity and Other Reactions to Light (Part ... energy, become photoexcited, generate ROS, and evoke cutaneous photosensitivity. The mechanism of porphyrin photosensitization is known to be photodynamic, or oxygen-dependent, and is mediated ... Photoallergic reactions require a similar management approach. Furthermore, patients with persistent light reaction and chronic actinic dermatitis must be meticulously protected against light...
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Chapter 057. Photosensitivity and Other Reactions to Light (Part 8) pot
... dioxide 25 Chapter 057. Photosensitivity and Other Reactions to Light (Part 8) Natural photoprotection is provided by structural proteins in the epidermis, particularly keratins and melanin. ... effects of long-term UV-B phototherapy and PUVA photochemotherapy mimic those seen in individuals with chronic sun exposure and include skin dryness, actinic keratoses, and an increased risk of ... Phototherapy and Photochemotherapy UV can also be used therapeutically. The administration of UV-B alone or in combination with topically applied agents can induce remissions of psoriasis and...
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Chapter 057. Photosensitivity and Other Reactions to Light (Part 3) doc
... including the face, the neck, and the hands. Major risk factors include male sex, childhood sun exposures, older age, fair skin, and residence at latitudes closer to the equator. Whites of darker complexions ... but this is likely due to failure to control for confounding factors such as sunscreen stability and frequency of application. Since no prospective studies are available to address this issue, ... both a tumor initiator and a promoter. The third and final step in the malignant process is malignant conversion of benign precursors into malignant lesions, a process thought to require additional...
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Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 7) doc
... prosody. Damage to perisylvian areas in the right hemisphere can interfere with speech prosody and can lead to syndromes of aprosodia. Damage to right hemisphere regions corresponding to Wernicke's ... specific patterns described in Table 27-1. In a patient Chapter 027. Aphasia, Memory Loss, and Other Focal Cerebral Disorders (Part 7) Gerstmann's Syndrome The combination of acalculia ... prosody, whereas damage to right hemisphere regions corresponding to Broca's area yields a greater impairment in the ability to introduce meaning-appropriate prosody into spoken language....
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Chapter 078. Prevention and Early Detection of Cancer (Part 7) pps
... screening and treatment on other disease outcomes (e.g., cardiovascular disease). In a randomized trial, two like populations are randomly established. One is given the medical standard of ... clinical Chapter 078. Prevention and Early Detection of Cancer (Part 7) Potential Biases of Screening Tests The common biases of screening are lead time, length-biased sampling, and selection. ... generally involve thousands of persons and last for years. Less definitive study designs are therefore often used to estimate the effectiveness of screening practices. After a randomized controlled...
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