Chapter 055 Immunologically Mediated Skin Diseases (Part 8) docx

... ineffective, use of aminoquinoline antimalarials may be indicated. Chapter 055. Immunologically Mediated Skin Diseases (Part 8) Lupus Erythematosus The cutaneous manifestations of lupus erythematosus ... evanescent, usually last for days and are often associated with exacerbations of systemic disease. Skin biopsy of acute lesions may show only a require treatment w...

Ngày tải lên: 07/07/2014, 01:20

... their skin disease, and is associated with the reappearance of IgA in their epidermal basement membrane zone. As in patients with celiac disease, dietary gluten sensitivity in Chapter 055. Immunologically ... patients with celiac disease, dietary gluten sensitivity in Chapter 055. Immunologically Mediated Skin Diseases (Part 5) Pemphigoid Gestationis Pemphigoid ges...

Ngày tải lên: 07/07/2014, 01:20

... photoprotective measures such as broad-spectrum sunscreens. Figure 55-3 Chapter 055. Immunologically Mediated Skin Diseases (Part 7) Dermatomyositis The cutaneous manifestations of dermatomyositis ... papules, heliotrope erythema, and poikiloderma serve to distinguish patients with dermatomyositis. Skin biopsy of erythematous, scaling lesions of dermatomyositis may reve...

Ngày tải lên: 07/07/2014, 01:20

... lesional or intact patient skin shows deposits of IgG on the surface of keratinocytes; deposits of complement components are typically found in lesional but not uninvolved skin. Deposits of IgG ... produce extensive denudation of the skin (Fig. 55-1). PV typically involves the mouth, scalp, face, neck, axilla, groin, and trunk. PV may be associated with severe skin pain; some patie...

Ngày tải lên: 07/07/2014, 01:20

... structure (e.g., penicillamine, captopril, enalapril) are most commonly Chapter 055. Immunologically Mediated Skin Diseases (Part 3) Pemphigus Foliaceus Pemphigus foliaceus (PF) is distinguished ... Castleman's disease; the latter is particularly common among children with PNP. In addition to severe skin lesions, many patients with PNP develop life-threatening bron...

Ngày tải lên: 07/07/2014, 01:20

... Chapter 055. Immunologically Mediated Skin Diseases (Part 4) Bullous Pemphigoid Bullous pemphigoid (BP) is a polymorphic ... lesional skin demonstrate subepidermal blisters and histologic features that roughly correlate with the clinical character of the particular lesion under study. Lesions on normal-appearing skin ... from other subepidermal blistering diseases...

Ngày tải lên: 07/07/2014, 01:20

... with inflammatory bowel disease (especially Crohn's disease). Chapter 055. Immunologically Mediated Skin Diseases (Part 6) Linear IgA Disease Linear IgA disease, once considered a ... that may be affected include the nasopharyngeal, laryngeal, esophageal, and anogenital mucosa. Skin lesions (present in about one-third of patients) tend to predominate on the scalp...

Ngày tải lên: 07/07/2014, 01:20

... microscopy of lesional skin is usually negative. Figure 55-7 Chapter 055. Immunologically Mediated Skin Diseases (Part 9) Figure 55-6 ... scleroderma. Skin biopsy reveals thickening of the dermis and homogenization of collagen bundles. Direct immunofluorescence microscopy of lesional skin is usually negative. Figure 55-7 Chapter 055. ... Scleroder...

Ngày tải lên: 07/07/2014, 01:20

... and therapeutic considerations. JAMA 284:350, 2000 [PMID: 10891967] Chapter 055. Immunologically Mediated Skin Diseases (Part 10) Scleroderma often eventuates in development of an expressionless, ... and inherited subepidermal blistering diseases: Advances in the clinic and the laboratory. Adv Dermatol 16:113, 2000 [PMID: 11094626] Sontheimer RD: Skin manifestatio ns...

Ngày tải lên: 07/07/2014, 01:20

... the manipulation, analysis, and characterization of DNA segments, is beyond the scope of this chapter. As these methods are widely used in genetics and molecular diagnostics, however, it is

Ngày tải lên: 07/07/2014, 01:20