... secondary manifestations of
Lyme disease, which is caused by the spirochete Borrelia burgdorferi. Her exposure pre-
sumably occurred on Cape Cod, a high-risk area of New England. Lyme disease occurs
in ... markings) suggestive of obstructive lung disease with loss of lung
tissue. Reduced expiratory air-flow rates are produced by narrowing of airways (e.g., in
asthma), loss of...
... with
resultant acidosis), it often is accompanied by a disturbance in acid-base balance. Addi-
son’s disease is possible, although it often is associated with orthostasis, some degree of
hypotension, and hyperkalemia ... state of hyperlipidemia
may accelerate atherosclerosis as well as the progression of further renal disease.
Patients often present with a hypercoagulable state due...
... creations of our own mind, the
problem of what it was that turned the one into the other vanishes completely.
4
The
society of the feudal ages con-tained all the germs of the society of the capitalist ... counterpart in the sphere of historical fact. Unfortunately, Max
Weber lent the weight of his great authority to a way of thinking that has no other basis than a
misuse...
... of competence in internal medicine.
Study of this self-assessment and review book should help
to (1) identify areas of relative weakness; (2) confirm areas
of expertise; (3) assess knowledge of ... representative of the major areas covered in Harrison’s
Principles of Internal Medicine, 15th ed., and (2) parallel
the format and degree of difficulty of the questions on the
e...
... majority
of patients with APML. The mechanism of action of this drug appears to be induction of
differentiation of the malignant clone. As such, patients enter remission slowly over a
period of 30 ... gait. MRI reveals
atrophy of both lobes of the cerebellum. Serologic eval-
uation reveals the presence of anti-Yo antibody. Which of
the following is the most likely cause o...
... its conversion to a disease-
causing isoform called PrP . The disease- causing isoform contains a high

- pleated sheet
Sc
content. The sporadic form of Creutzfeldt-Jakob disease is most common; ... The patient has no history
of alcohol abuse, thyroid disease, risk factors for athero-
sclerotic heart disease, or family history of hemochro-
matosis. In considering a potential eti...