Chapter 054 Skin Manifestations of Internal Disease (Part 2) ppt

Chapter 054. Skin Manifestations of Internal Disease (Part 2) ppt

... Associated with Parkinson's Skin biopsy Topical glucocorticoids and imidazoles to psoriasis. It is also important to examine the skin carefully for a migration of the erythema and associated ... history of atopy, including Skin biopsy Topical glucocorticoids, tacrolimus, pimecrolimus, tar, and Contact Local: Erythema, crusting, vesicles, and bullae Depends on offending ... Generalized, but characteristic "skip" areas of normal skin Wax-like keratoderma Exclude cutaneous T cell lymphoma Skin biopsy Isotretinoin or acitretin; methotrexate...

Chapter 054. Skin Manifestations of Internal Disease (Part 5) pptx

... diseases A. Migratory 1. Erythema migrans 2. Urticaria (≤10% of cases) 3. Erythema gyratum repens 4. Erythema marginatum 5. Pustular psoriasis Chapter 054. Skin Manifestations of ... the scarring lesions of discoid lupus can be seen in patients with systemic lupus, in the majority of cases the disease process is limited to the skin. Less common causes of scarring alopecia ... Scattered, poorly circumscribed patches of alopecia with a "moth-eaten" appearance are a manifestation of the secondary stage of syphilis. Diffuse thinning of the hair is also associated with...

Chapter 054. Skin Manifestations of Internal Disease (Part 8) ppt

... decreased activity will acquire some pigmentation of the eyes, hair, and skin as they age. The degree of pigment formation is also a function of racial background, and the pigmentary dilution ... bleed. Hypopigmentation (Table 54-9) Disorders of hypopigmentation are often classified as either diffuse or localized. The classic example of diffuse hypopigmentation is oculocutaneous albinism ... patients with type IA OCA have a total lack of enzyme activity. At birth, different forms of OCA can appear similar—white hair, gray-blue eyes, and pink-white skin. However, the patients with no tyrosinase...

Chapter 054. Skin Manifestations of Internal Disease (Part 9) ppt

... ultraviolet B. Chapter 054. Skin Manifestations of Internal Disease (Part 9) aAbsence of melanocytes. bNormal number of melanocytes. cPlatelet storage defect and restrictive lung disease secondary ... perifollicular macules of normal pigmentation are seen within areas of depigmentation. The basis of this leukoderma is unknown; there is no evidence of inflammation in areas of involvement, but ... (types I and II). Diseases of the thyroid gland are the most frequently associated disorders, occurring in up to 30% of patients with vitiligo. Circulating autoantibodies are often found, and...

Chapter 054. Skin Manifestations of Internal Disease (Part 11) pptx

... location as circular areas of erythema that can become bullous and then resolve as brown macules. The eruption usually appears within hours of administration of the offending agent, and common ... discoloration of the shins, hard palate, and face, while blue macules (often misdiagnosed as bruises) can be seen on the lower extremities and in sites of endocrine overactivity in the form of Cushing's ... patients receiving bleomycin often have hyperpigmentation overlying the elbows, knees, and small joints of the hand. Localized hyperpigmentation is seen as a side effect of several other systemic...

Chapter 054. Skin Manifestations of Internal Disease (Part 14) pptx

... but the base of the lesion is purpuric or necrotic, and it may develop into an ulcer (see "Purpura," below). Chapter 054. Skin Manifestations of Internal Disease (Part 14) eAlso ... drugs. A rapid diagnosis of SSSS versus TEN can be made by a frozen section of the blister roof or exfoliative cytology of the blister contents. In SSSS the site of staphylococcal infection ... areas of erythema and then slough. This results in large areas of denuded skin. The associated morbidity, such as sepsis, and mortality are relatively high and are a function of the extent of...

Chapter 054. Skin Manifestations of Internal Disease (Part 21) pptx

... more often than those with Hodgkin disease, and occasionally, the skin nodules precede the development of extracutaneous non-Hodgkin lymphoma or represent Chapter 054. Skin Manifestations of Internal ... have the form of lupus that is limited to the skin. However, 2–10% of these patients eventually develop systemic lupus. Direct immunofluorescence of involved skin shows deposits of IgG or IgM ... Lymphoma cutis can occur anywhere on the surface of the skin, whereas the sites of predilection for lymphocytomas include the malar ridge, tip of the nose, and earlobes. Patients with non-Hodgkin...

Chapter 054. Skin Manifestations of Internal Disease (Part 1) potx

... Internal Disease (Part 1) Harrison's Internal Medicine > Chapter 54. Skin Manifestations of Internal Disease Skin Manifestations of Internal Disease: Introduction It is now a generally ... Reiter's disease e. Sarcoidosisd aDiscussed in detail in Chap. 53. bAssociated with chronic sun exposure and exposure to arsenic. Chapter 054. Skin Manifestations of Internal Disease (Part ... a generally accepted concept in medicine that the skin can show signs of internal disease. Therefore, in textbooks of medicine one finds a chapter describing in detail the major systemic disorders...

Chapter 054. Skin Manifestations of Internal Disease (Part 3) pot

... Chapter 054. Skin Manifestations of Internal Disease (Part 3) Drug-induced erythroderma (exfoliative dermatitis) may begin ... 25% of the cases of erythroderma were due to CTCL. The patient may progress from isolated plaques and tumors, but more commonly the erythroderma is present throughout the course of the disease ... stage of the disease. Alopecia (Table 54-4) The two major forms of alopecia are scarring and nonscarring. In scarring alopecia there are associated fibrosis, inflammation, and loss of hair...

Chapter 054. Skin Manifestations of Internal Disease (Part 4) pdf

... associated diseases: hyperthyroidism, hypothyroidism, Topical anthralin; intralesional glucocorticoids; topical contact sensitizers Chapter 054. Skin Manifestations of Internal Disease (Part ... circular areas of hair loss, 2–5 cm in diameter In extensive cases, coalescence of lesions and/or involvement of other hair-bearing surfaces The germinative zones of the hair follicles ... female pattern) midline of the scalp Recession of the anterior scalp line in men and some women affected hairs to the effects of testosterone Increased levels of circulating androgens...

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