Chapter 050 Hirsutism and Virilization (Part 3) ppt
Chapter 050. Hirsutism and Virilization (Part 3) ppt
... after menopause.
Figure 50-2
Chapter 050. Hirsutism and
Virilization
(Part 3)
Hormonal Evaluation
Androgens are secreted by the ovaries and adrenal glands in response to
their respective ... (LH) and
adrenocorticotropic hormone (ACTH).
The principal circulating steroids involved in the etiology of hirsutism are
testosterone, androstenedione, and dehydroepia...
Chapter 050. Hirsutism and Virilization (Part 1) pptx
... clitoromegaly, and increased libido; virilization is
an ominous sign that suggests the possibility of an ovarian or adrenal neoplasm.
Table 50-1 Causes of Hirsutism
Gonadal hyperandrogenism
... Diazoxide
Cyclosporine
True hermaphroditism
Virilization refers to a condition in which androgen levels are sufficiently high to
cause additional signs and symptoms such as deepeni...
Chapter 050. Hirsutism and Virilization (Part 2) docx
... presenting with hirsutism. This assessment
permits the distinction between hirsutism and hypertrichosis and provides a
baseline reference point to gauge the response to treatment. A simple and
commonly ... eyelashes, and vellus hairs are androgen-
insensitive, whereas the axillary and pubic areas are sensitive to low levels of
androgens. Hair growth on the face, chest, upper...
Chapter 050. Hirsutism and Virilization (Part 4) ppsx
... androgen synthesis and action: (1) suppression of adrenal and/ or
ovarian androgen production; (2) enhancement of androgen-binding to plasma-
binding proteins, particularly SHBG; (3) impairment of ... hyperandrogenism.
Because adrenal androgens are readily suppressed by low doses of
glucocorticoids, the dexamethasone androgen-suppression test may broadly
distinguish ovarian from adren...
Chapter 050. Hirsutism and Virilization (Part 5) pot
... on hirsutism have been reported, but the predominance of 5α-
reductase type 1 in the PSU appears to account for its limited efficacy. Finasteride
Chapter 050. Hirsutism and
Virilization
(Part ... SHBG
levels and in their androgenic potential. Ethynodiol diacetate has relatively low
androgenic potential, whereas progestins such as norgestrel and levonorgestrel are
particu...
Chapter 023. Weakness and Paralysis (Part 3) ppt
... junction.
Chapter 023. Weakness and Paralysis
(Part 3)
Lower Motor Neuron Weakness
This pattern results from disorders of cell bodies of lower motor neurons in
the brainstem motor nuclei and ... tone and attenuates the stretch
reflexes elicited on examination. An absent stretch reflex suggests involvement of
spindle afferent fibers.
Figure 23-2
variable in degree and...
Chapter 026. Confusion and Delirium (Part 3) pptx
... 1990.
History
Chapter 026. Confusion and Delirium
(Part 3)
Approach to the Patient: Delirium
As the diagnosis of delirium is clinical and made at the bedside, a careful
history and physical ... autonomic instability, and changes in affect
Table 26-1 The Confusion Assessment Method (CAM) Diagnostic
Algorithm
The diagnosis of delirium requires the presence of features 1...
Chapter 035. Hypoxia and Cyanosis (Part 3) ppt
... Chapter 035. Hypoxia and Cyanosis
(Part 3)
Adaptation to Hypoxia
An important component of the respiratory response ... cells in the carotid and aortic bodies and in the
respiratory center in the brainstem. The stimulation of these cells by hypoxia
increases ventilation, with a loss of CO
2
, and can lead to respiratory ... be subdivided into central and peripheral typ...
Chapter 053. Eczema and Dermatitis (Part 3) pptx
... form crusts and heal.
Chapter 053. Eczema and
Dermatitis
(Part 3)
Lichen Simplex Chronicus
Lichen simplex chronicus may represent the end stage of a variety of
pruritic and eczematous ... Dyshidrotic eczema, a variant of hand eczema, presents with
multiple, intensely pruritic, small papules and vesicles occurring on the thenar and
hypothenar eminences and the sid...
Chapter 080. Cancer Cell Biology and Angiogenesis (Part 3) ppt
... before the clinical utility of this approach can be fully realized.
Chapter 080. Cancer Cell Biology
and Angiogenesis
(Part 3)
Figure 80-1
... (which binds and inhibits p 53) was deleted; this virus selectively replicates
in tumor cells lacking p53 function.
This virus has shown efficacy in phase II clinical trials of head and neck
tumors, ... deleted and the ot...