Chapter 050 Hirsutism and Virilization (Part 2) docx

... presenting with hirsutism. This assessment permits the distinction between hirsutism and hypertrichosis and provides a baseline reference point to gauge the response to treatment. A simple and commonly ... eyelashes, and vellus hairs are androgen- insensitive, whereas the axillary and pubic areas are sensitive to low levels of androgens. Hair growth on the face, chest, upper...

Ngày tải lên: 06/07/2014, 20:20

... after menopause. Figure 50-2 Chapter 050. Hirsutism and Virilization (Part 3) Hormonal Evaluation Androgens are secreted by the ovaries and adrenal glands in response to their respective ... (LH) and adrenocorticotropic hormone (ACTH). The principal circulating steroids involved in the etiology of hirsutism are testosterone, androstenedione, and dehydroepiand...

Ngày tải lên: 06/07/2014, 20:20

... the steps in the pathway of androgen synthesis and action: (1) suppression of adrenal and/ or ovarian androgen production; (2) enhancement of androgen-binding to plasma- binding proteins, particularly ... hyperandrogenism. Because adrenal androgens are readily suppressed by low doses of glucocorticoids, the dexamethasone androgen-suppression test may broadly distinguish ovarian from...

Ngày tải lên: 06/07/2014, 20:20

... on hirsutism have been reported, but the predominance of 5α- reductase type 1 in the PSU appears to account for its limited efficacy. Finasteride Chapter 050. Hirsutism and Virilization (Part ... SHBG levels and in their androgenic potential. Ethynodiol diacetate has relatively low androgenic potential, whereas progestins such as norgestrel and levonorgestrel are particu...

Ngày tải lên: 06/07/2014, 20:20

... clitoromegaly, and increased libido; virilization is an ominous sign that suggests the possibility of an ovarian or adrenal neoplasm. Table 50-1 Causes of Hirsutism Gonadal hyperandrogenism ... Diazoxide Cyclosporine True hermaphroditism Virilization refers to a condition in which androgen levels are sufficiently high to cause additional signs and symptoms such as deepeni...

Ngày tải lên: 06/07/2014, 20:20

... heat stroke typically occurs in individuals exercising at elevated ambient Chapter 017. Fever and Hyperthermia (Part 2) Hyperthermia Although most patients with elevated body temperature ... prescription psychotropic drugs and illicit drugs. Drug-induced hyperthermia may be caused by monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and amphetamines and b...

Ngày tải lên: 06/07/2014, 12:20

... (granulocyte colony-stimulating factor) and GM-CSF (granulocyte- macrophage colony-stimulating factor) are critical to this process. Identifying cellular characteristics and specific cell-surface markers ... maturational stage. Figure 61-3 Neutrophil band with Döhle body. The neutrophil with a sausage-shaped nucleus in the center of the field is a band form. Döhle bodies are...

Ngày tải lên: 07/07/2014, 01:20

... infected people are rejected by family and friends, leaving them this chronic condition alone. 4. With his left hand he snatched the gun from the man's hands, and with his right he gave him a ... bay. In winter it could be very nasty because of strong winds and sea spray. In fact, when a gale was blowing, Norah and her husband got used to sleeping in a small room downstairs...

Ngày tải lên: 23/12/2013, 11:15

... decrease, and stability. For example, Austria and Spain reveal a period of stability until the end of the 1990s and a marked decline thereafter. In their turn, countries like Ireland, Luxembourg, and ... sources and amending and subsequently repealing Directives 2001/77/EC and 2003/30/EC. Fang, W-S. & Miller, S. M. (2008). The Great Moderation and the Relationship bet...

Ngày tải lên: 19/06/2014, 08:20

...    (39) with T in K and e si in hPa. Other equations have also been widely used (Murray, 1967; Hyland and Wexler, 1983; Marti and Mauersberger, 1993; Murphy and Koop, 2005). Water evaporates ... holds for δq=0, where c p and c v are respectively the specific heats at constant pressure and constant volume, p and v are the specific pressure and volume, and δq is t...

Ngày tải lên: 19/06/2014, 08:20