Chapter 017 Fever and Hyperthermia (Part 6) doc
Chapter 017. Fever and Hyperthermia (Part 6) doc
... 9751057] Chapter 017. Fever and Hyperthermia (Part 6) Regimens for the Treatment of Fever The objectives in treating fever are first to reduce the elevated hypothalamic set point and second ... Reducing fever with antipyretics also reduces systemic symptoms of headache, myalgias, and arthralgias. Oral aspirin and NSAIDs effectively reduce fever but can adversely affect platelets and ... preparations of NSAIDs and rectal suppository preparations of various antipyretics can be used.Treatment of fever in some patients is highly recommended. Fever increases the demand for oxygen (i.e.,...
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Chapter 017. Fever and Hyperthermia (Part 1) docx
... time; however, shivering is not Chapter 017. Fever and Hyperthermia (Part 1) Harrison's Internal Medicine > Chapter 17. Fever and Hyperthermia Fever and Hyperthermia: Introduction Body ... ovulation and remains at that level until menses occur. Body temperature can be elevated in the postprandial state. Pregnancy and endocrinologic dysfunction also affect body temperature Fever ... also affect body temperature Fever versus Hyperthermia Fever Fever is an elevation of body temperature that exceeds the normal daily variation and occurs in conjunction with an increase in...
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Chapter 017. Fever and Hyperthermia (Part 2) docx
... individuals exercising at elevated ambient Chapter 017. Fever and Hyperthermia (Part 2) Hyperthermia Although most patients with elevated body temperature have fever, there are circumstances in ... increased thermogenesis. It is important to distinguish between fever and hyperthermia since hyperthermia can be rapidly fatal and characteristically does not respond to antipyretics. In an ... prescription psychotropic drugs and illicit drugs. Drug-induced hyperthermia may be caused by monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and amphetamines and by the illicit use...
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Chapter 017. Fever and Hyperthermia (Part 3) pot
... required for fever production. Chapter 017. Fever and Hyperthermia (Part 3) Pathogenesis of Fever Pyrogens The term pyrogen is used to describe any substance that causes fever. Exogenous ... encoded by a separate gene, and each pyrogenic cytokine has been shown to cause fever in laboratory animals and in humans. When injected into humans, IL-1 and TNF produce fever at low doses (10–100 ... of fever are illustrated in Fig. 17-1. As has been mentioned, several cell types can produce pyrogenic cytokines. Pyrogenic cytokines such as IL-1, IL-6, and TNF are released from the cells and...
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Chapter 017. Fever and Hyperthermia (Part 4) potx
... Chapter 017. Fever and Hyperthermia (Part 4) Chronology of events required for the induction of fever. AMP, adenosine 5'-monophosphate; ... prostaglandin E2; TNF, tumor necrosis factor.There are four receptors for PGE2, and each signals the cell in different ways. Of the four receptors, the third (EP-3) is essential for fever: ... deleted in mice, no fever follows the injection of IL-1 or endotoxin. Deletion of the other PGE2 receptor genes leaves the fever mechanism intact. Although PGE2 is essential for fever, it is not...
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Chapter 017. Fever and Hyperthermia (Part 5) pdf
... membrane, and this release is the rate-limiting step in the synthesis of PGE2. Therefore, inhibitors of cyclooxygenase are potent antipyretics. Chapter 017. Fever and Hyperthermia (Part 5) Fever ... typhoid fever and disseminated tuberculosis. Temperature-pulse dissociation (relative bradycardia) occurs in typhoid fever, brucellosis, leptospirosis, some drug-induced fevers, and factitious fever. ... disease and other lymphomas. In cyclic neutropenia, fevers occur every 21 days and accompany the neutropenia. There is no periodicity of fever in patients with familial Mediterranean fever. ...
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Chapter 040. Diarrhea and Constipation (Part 6) doc
... empirical Rx before evaluation with (*) metronidazole and with (t) quinolone. WBCs, white blood cells. Chapter 040. Diarrhea and Constipation (Part 6) OTHER CAUSES Side effects from medications ... depends on its severity and duration and on various host factors (Fig. 40-2). Most episodes of acute diarrhea are mild and self-limited and do not justify the cost and potential morbidity of ... antacids, and laxatives. Occlusive or nonocclusive ischemic colitis typically occurs in persons >50 years; often presents as acute lower abdominal pain preceding watery, then bloody diarrhea; and...
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Chapter 046. Sodium and Water (Part 6) docx
... Chapter 046. Sodium and Water (Part 6) Hyponatremia in the setting of ECF volume expansion is usually associated ... Na+ and water), and diuretic therapy. The degree of hyponatremia often correlates with the severity of the underlying condition and is an important prognostic factor. Oliguric acute and chronic ... deficiency may cause hyponatremia. Adrenal insufficiency (Chap. 3 36) and hypothyroidism (Chap. 335) may present with hyponatremia and should not be confused with SIADH. Although decreased mineralocorticoids...
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Chapter 059. Bleeding and Thrombosis (Part 6) doc
... thrombin-activatable fibrinolysis inhibitor; TFPI, tissue factor pathway inhibitor. Chapter 059. Bleeding and Thrombosis (Part 6) Underlying Systemic Diseases that Cause or Exacerbate a Bleeding Tendency ... malignancy, medications such as hormonal therapy, obesity, and genetic predispositions. Factors that increase risks for venous and both venous and arterial thromboses are shown in Table 59-3. Age ... Coagulation factors II, VII, IX, X and proteins C, S, and Z are dependent on vitamin K for posttranslational modification. Although Vitamin K is required in both procoagulant and anticoagulant processes,...
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Chapter 061. Disorders of Granulocytes and Monocytes (Part 6) doc
... Chapter 061. Disorders of Granulocytes and Monocytes (Part 6) Hereditary Neutropenias Hereditary neutropenias are rare and may manifest in early childhood ... increased production and increased marrow release. Increased production is also associated with chronic inflammation and certain myeloproliferative diseases. Increased marrow release and mobilization ... 10,000–25,000/µL occurs in response to infection and other forms of acute inflammation and results from both release of the marginated pool and mobilization of marrow reserves. Persistent neutrophilia...
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