History of Economic Analysis part 24 pptx

... one of the most powerful hallucinogenic drugs of abuse. LSD was explosively abused in U.S.A. in the latter half of the 1960s. In Japan, the amount of seizure of LSD is much smaller than that of ... hallucinogenic activity of LSD was con rmed by Albert Hofmann who did synthesize the compound; the pharmaco- logical activity can be obtained by oral administration of as small a...

Ngày tải lên: 08/11/2013, 01:15

... 2.2 HPLC and LC/MS analysis 269 Notes a) When GC/MS, HPLC and LC/MS are compared for analysis of haloperidol and bromperi- dol, the LC/MS seems of the best choice for their trace analysis.  e HPLC ... mode of GC/MS is employed using ions at m/z 224 for haloperidol and m/z 268 for bromperidol; peak area ratios of haloperi- dol or bromperidol to IS are plotted against various co...

Ngày tải lên: 15/12/2013, 12:15

... She had no history of smok- ing, and had quitted drinking alcohol since the appearance of the epileptic attack. Upon medi- cal examination for admission to a hospital, she complained of her bad ... steam of nitrogen with warming at 40 °C. vi.  e residue is dissolved in 100 µL of the mobile phase. vii. A  xed amount of the solution is injected into HPLC. viii. For construction...

Ngày tải lên: 15/12/2013, 12:15

... Preparation of the monocholine ester of succinic acid and some related derivatives. J Am Chem Soc 75:4725–4727 3) The Pharmaceutical Society of Japan (ed) (1992) Standard Methods of Chemical Analysis ... condensation of the eluate, there is a possibility of loss of the analyte due to its adsorption to the glassware. It is preferable to use a plastic container for condensat...

Ngày tải lên: 24/12/2013, 18:15

... contained. During preparation of the solutions and also during analysis, there is a possibility of decomposition of the hypochlorite ion. As shown in > Figure 1.1, the peaks of such decomposition ... be used for general analysis of negative ions, including cyanide, azide and arsenate [1, 2]; the conditions can be also applied to chlorate and analogous anions.  e pH of t...

Ngày tải lên: 24/12/2013, 18:15

... shows faster blood clearance of the trans-form of permethrin than that of the cis-form in humans.  e metabolic rate of the trans-form of permethrin is faster than that of the cis-form also in ... in agreement with those of the patient. Notes a)  e structures of the cis- and trans-forms of permethrin are due to di erent locations of the dichlorovinyl group and of th...

Ngày tải lên: 24/12/2013, 18:15

... reports on nail analysis are not many, its usefulness seems comparable to that of hair analysis, in view of identi cation ability of a drug previously administered and estimation of both amount ... of abuse in meconium of newborn infants. J Anal Toxicol;18:41–45 27) Moriya F, Chan K-M, Noguchi TT et al. (1995) Detection of drugs -of- abuse in meconium of a stillborn bab...

Ngày tải lên: 22/01/2014, 00:20

... registrants of the ml-anal were composed of the members of ml-poison who were interested in the analysis, engineers of manufacturers of analytical instruments and attendees of the short course of the ... serum; but the participants counted 38 only.  e cause of the decrease of partici- pants might be due to that the tests were almost the same as those of the previous ye...

Ngày tải lên: 22/01/2014, 00:20

... [3] opened two packages of naphthalene (commercial name: Neopas ® ) and seemed to ingest a part of the total amount (18 g) of the compound, because an appreciable amount of its crystals were found ... naphthalene concentration g . Assessment of the method > Figure 6.1 shows mass spectra of naphthalene and IS. By this method, most reliable identi-  cation of naphthalene ca...

Ngày tải lên: 22/01/2014, 00:20

... detection. Abstracts of the 116th Annual Meeting of the Pharmaceutical Society of Japan, p 188 (in Japanese) 11) Fukushima S (1996) Analysis of tetrodotoxin in specimens of poisoned victims. ... urine specimens of poisoned patients. In this chapter, the methods of analysis of tetrodotoxin in human specimens by GC/MS and HPLC are described [3]. ⊡ Table 3.1 Incidence of...

Ngày tải lên: 22/01/2014, 00:20