Pharmaceutical Substances Syntheses, Patents, Applications - Part 98 pdf
Pharmaceutical Substances Syntheses, Patents, Applications - Part 98 pdf
...
2-[ [[ 1-( 4-chlorobenzoyl )-5 -methoxy-2-methyl-1H-indol-3-yl]acetyI]arnino ]-2 -deoxy-~-glucose
indornetacin
(9.
v.)
1
-( 4-chlorobenzoyl )-2 -
methyl-5-methoxyindol-
3-acetyl chloride
(I)
...
ethyl 2-( 2-methyl-
3.4.6-trifluorobenzayl )-
3-etho~yacr~late
ethyl 2-( 2-methyl-
3.4.6-trifluorobenzoy1 )-
3-cyclopropylamino-
acrylate
(11)
ethyl
1
-c...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 12 pdf
...
(111)
4-pyridyl-
molonoldehyde
1.2-dihydro- 2-0 x 0-
5-( 4-pyridyl).
nicotinic acid
3-nitro- 5-( 4-pyridyl )-
Z(1H)-pyridinone
(IV)
120
A
Anastrozole
synthesis of
ethyl
N-(2,3-dichloro-6-aminobenzy1)glycinate: ... ester
2,3-dkhloro-
6-nitro-
benzonitrile
ethyl N-(2,3-dichloro- 6-
diphenyl N-cyano- ethyl (2-cyonoimino-5, 6-
orninobenzyi)glycinote irnidoc...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 16 pdf
...
4-methyl- 2-
nitrooniline
3-dimethylomino- 7-
methyl-1,2-dihydro-
1,2,4-benzotriozine
(I)
NC,
P43
HZ, Roney-Ni
Y
4
b
I
CH,
dimethyl-
3-dimethylomino-7methyl-
cyonomide 1,2,4-benzotriozine ... 5 2-8 8-0 MF: Cl,H,,N,O, MW: 366.41 EINECS: 20 0-1 5 6-1
LD,,: 9300
pglkg (M, i.v.); 1320 mglkg (M, p.0.);
1902 mgkg (R, p.0.)
CN:
endo-(f )-3 -( 3-hydroxy-l-oxo-2-...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 38 pdf
...
ylthio)methyl ]-5 -thia-l-azabicyclo[4.2.0]oct-2-ene-2-carboxylic
acid
7-orninocepholo- 4-mercopto-
sporonic acid 1,Z.J-triozole
7(R)-omino- 3-[ (I ,2, 3-
triozol-4-ylthio)methyl ]-
3-cephern-4-corboxylic ...
RN:
5618 7-4 7-4 MF: C18H,5CI,N505S, MW: 548.45
CN:
(6R-trans )-7 -[ [(3,5-dichloro-4-oxo-l(4H)-pyridinyl)acetyI]amino ]-3 -[ [(5-methyl-1,3,4-thiadiazol-...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 55 pdf
...
RN: 11 1 0-4 0-3 MF: C3,H3,N20s MW: 530.67 EINECS: 21 4-1 7 5-8
CN:
(11~,16a )-2 1-( acetyloxy)-ll,17-dihydroxy-6,16-dimethyl-2'-phenyl-2'H-pregna-2,4,6-trieno[3, 2-
clpyrazol-20-one
Codeine ... 50 8-7 5-8 MF: C,H,,O,,, MW: 550.65 EINECS: 20 8-0 8 6-3
LD,,,:
1 mglkg (M, i.v.); >2 glkg (M, p.0.);
15.2 mg/kg (R, i.v.)
CN:
(3~,5~ )-3 -[ (6-deoxy-a...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 67 pdf
...
2-mothyl-5,6,7, 8- 4-methylbenzyl- 2-methyl-1 -( 4-methyl-
tctrahydroisoquino- mognesium chloride benzyl )-1 .2.5.6.7, 8-
linium bromide hexohydroisoquinoline
(+ )-2 -methyl- 1-( 4-
methylbenzy1 )- ... 566 7-4 6-9 MF: C2,H2,N0,. H,PO, MW: 449.44 EINECS: 22 7-1 2 6-0
4-( 2-aminopropyl )-
1.2-dimethoxybenzene
(I)
19 0-2 00
OC POCI,
___,
n
COOH...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 82 pdf
...
5294 2-3 1-1 MF:
C,9H28CINS0
MW:
377.92
CN:
2-[ 3-[ 4-( 3-chlorophenyl )-1 -piperazinyl]propyl ]-4 ,5-diethyl-2,4-dihydro-3H-1,2,4-triazol-3-one
4,5-diethyl-
1
-bromo- 3-
2-( 3-chloropropyl )-
b 5-1 ... chlarobenzayl )-
5-ethylthiophene
CH3COOH, pyridine
-
H\ 1-
\
phosphorus
-
NH2
(I)
5-( 2-ch1orophenyl )-
(11)
1.3-dihydro-
7...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 83 pdf
...
4-( 3-formylpropyl )-
carbonyl)propyl ]-
hydride
1
-( trimethylsilyl )-
1H-imidazale imidozole (111)
4-( tert-butyl- 4-[ 4-[ 4-( tert-butyl-
carbamoy1 )-1
-
carbomoyl)-phenyll- 4-
bromobenzene hydroxybutyl ]-1 -( trimethyl- ...
[5R-[3(R*),5a,6a(R*)] ]-6 -( l-tlydroxyethyl )-7 -oxo- 3-( tetrahydro-2-furmyl )-4 -thia-l-azabicyclo[3.2.O ]...
Pharmaceutical Substances Syntheses, Patents, Applications - Part 89 pdf
...
per-
2-nitro-5-fluoro-
mongonote
fluorotoluene benzoic
acid
HOOC
ethyl
isocyanate-
0
CH3 ocetote
potossium tert-butylate
N-methyl- 7-fluoro-4-methyl-
glycine 3,4-dihydro-2H-1. 4-
benzodiazepin-2,5(1H )- ...
8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[l,5-a][1,4]be1uodiazepine-3-carhoxylic
acid ethyl
ester
1.
Hz.
Pd-C
KMnO 2. COC12
F
CH3 potassium
F
COOH
2....
Pharmaceutical Substances Syntheses, Patents, Applications - Part 99 pdf
...
RN:
5 5-6 5-2 MF: C,,H,,N,
MW:
198. 31 EINECS: 20 0-2 4 1-3
chloro- octahydro- octohydro-
acetonitrile azocine ozocine- 1
-
ocetonitrile
1
-( 2-amino-
ethy1)octa-
hydroozocine
(I)
S-methylthio- ...
pyrocotechol epichlorohydrin 2-hydroxymethyl- 2-chloromethyl-
2.3-dihydro-
2.3-dihydro-
1.4-benzodioxin 1,4-benzodioxin
(I)
benzylomine 2-ominomethyl-
2,3-dihydro...
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