NOVEL APPROACHES AND THEIR APPLICATIONS IN RISK ASSESSMENT

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... reported in Japan in the late 1970’s), whereas currently diarrheic shellfish toxin outbreaks are documented all over the world. Tens of thousands cases of intoxication have been reported (Picot ... Yndestad, 1993). Based on the LOAEL of 1.0 μg OA/kg bw and a chosen safety factor of 3 because of documented human cases involving more than 40 people and because DSP symptoms are readily reve...

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