... resorption in men much more strongly than testoster-one [58]. In this short-term study (3 weeks), it could also be shown that 17-estradiol and, to a lesser extent, testosterone are direct stimulators ... mainly ICTP, bone ALP, NTX and - -CTX (native non-isomerized CTX-I reflecting the most recently synthesized type I collagen molecules) and, to a lesser extent, P1NP, -CTX or OC [70]. In these patients, ... osteoporosis. This second edition of Osteoporosis in Men is, thus, timely. In the second edition, we have made major additions to reflect increased areas of new knowledge, including genet-ics and inherited...