... paclitaxel, and we use gene expression profiling to identify genes and pathways that may be important to the development of drug resistance in ovarian cancer. Methods Cell line and generation of ... cross-resistance to paclitaxel, and the paclitaxel-derived resistant cells (OV90P-3 and OV90P-7) were resistant to both cisplatin and doxorubicin (Figure 1A). Microarray...
Ngày tải lên: 20/06/2014, 08:20
... concluded: f 1 f 2 ¼ ffiffiffiffiffiffiffiffi J 2 l 2 J 1 l 1 s ð4Þ where f 1 and f 2 are the frequencies, J 1 and J 2 the angular moments of inertia of the metal paddles, and l 1 and l 2 the length of nanotubes in torsional oscillators 1 and 2, respectively. ... which has a density of 19,300 kg/m 3 . The dimensions of the metal paddle are: length of 4.18 nm, width of 10.0 nm, and t...
Ngày tải lên: 22/06/2014, 22:20
Tài liệu Báo cáo khoa học: Molecular modeling and functional characterization of the monomeric primase–polymerase domain from the Sulfolobus solfataricus plasmid pIT3 doc
... plausibly involved in DNA recognition and binding and is positioned left of the active site [14]. Rep245 is both capable of de novo synthesis of DNA primers and of elongating them. Long DNA extension ... presence of 0.2 mm dNTPs and 0.5 U of Taq DNA polymerase (Promega). To analyze the effect of temperature on primase activity, Rep245 and Rep516 proteins were i...
Ngày tải lên: 18/02/2014, 18:20
báo cáo hóa học:" Species distribution and antimicrobial susceptibility of gram-negative aerobic bacteria in hospitalized cancer patients" pdf
... contributions HMA and AE contributed to conception and design, pro- vision of study materials or patients, collection and assembly of data, data analysis and interpretation and manuscript writing. ... The clinical significance of positive blood cul- tures in the 1990s: a prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bactere- mia...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "Biomedical informatics and translational medicine Indra Neil Sarkar" pot
... and specialization of existing and new clinical and public health informatics techniques within the context of implementation and controlled assess- ment of novel interventions, development of ... molecular and cellular basis of disease[19-25]. Imaging informatics tech- niques are needed for the development and analysis of visualization approaches for understand ing...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "Future research and therapeutic applications of human stem cells: general, regulatory, and bioethical aspects" ppt
... safety and efficacy of cell therapy pro- ducts. The greater the understanding of the biology of stem cell self-renewal and differentiation, the more pre- cise the evaluation and prediction of potential ... processing; iv) specific and detailed determination of the type of cells forming the product and what are their exact purity and potency; v) in vivo safety and eff...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Factor structure and internal consistency of the 12-item General Health Questionnaire (GHQ-12) and the Subjective Vitality Scale (VS), and the relationship between them: a study from France" potx
... values of 0.80 and 0.89. The results of confirmatory factor analysis of the three-factor model of the GHQ-12Figure 1 The results of confirmatory factor analysis of the three-factor model of the ... investigator and analysed the data and wrote the first draft. AI and CR contributed to the study design and the analysis. AM contributed to the analysis and wrote t...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: "Toe clearance and velocity profiles of young and elderly during walking on sloped surfaces" potx
... median and IQR of MTC and Vel MTC for the young and elderly group walking at (a) -3°, (b) 0° and (c) +3° slopes. *significance at p < 0.01. Khandoker et al. Journal of NeuroEngineering and ... years of age. Journal of Rehabilitation Research and Development 1993, 30:210-223. doi: 10.1186/1743-0003-7-18 Cite this article as: Khandoker et al., Toe clearance and veloci...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: " Leader (L) and L* proteins of Theiler''''s murine encephalomyelitis virus (TMEV) and their regulation of the virus'''' biological activities" docx
... 1988, 165:1-12. 6. Michiels T, Jarousse N, Brahic M: Analysis of the leader and cap- sid coding regions of persistent and neurovirulent strains of Theiler's virus. Virology 1995, 214:550-558. 7. ... pitfall of L* in studies such as these involving L* is that the sequence of L* overlaps with that of polyprotein (L and a part of P1). Therefore, it is impossible to eva...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx
... role of CCR1 and its ligand CCL3 in the pathogenesis of MS [39,40,42] and EAE [22,44,46], have provided evidence for an important role of CCR1 in MS and EAE. Histopathological features of MOG-EAE ... purposes) macrophages and resident microglia to sites of CNS inflammation. Detailed knowledge of expression patterns is crucial for the understanding of therapeutic modulati...
Ngày tải lên: 19/06/2014, 22:20