... repeated. Substitution of the 21-bp repeatelement with unrelated sequence of the same length, how-ever, was observed to ablate the replicative advantage,thus indicating that the 21-bp triplication ... wereidentified for the transcription factor, c-Myb, that crossed the repeat junctions of the triplication. Further, once c-Myb was bound to the triplication, the transcriptional co-activator CBP ... grant from the Cancer Association of Greater New Orleans. The authors grate-fully acknowledge Drs. Matthew Burow and Linda Wolff for helpful discus-sions and for the gift of reagents. Patricia...