... immunization) of EAE show extensive inflammation involving the white and grey matter (D), with marked demyelination in the inflammatory areas (F). The majority of the infiltrating inflammatory ... apoptosis of infiltrating cells in the CNS of animals with EAE [80]. The limitation of inflammationseen in the CNS could also be the result of a diminishedantigen-presenting capability. In conclusion, ... capable of phagocytosing myelin and damaging axons. In this study, wecharacterize the regional, temporal and cellular expression of CCR1, CCR2 and CCR5 mRNA in the spinal cord of ratswith myelin...