... complex remain to be identified.Binding of the NgR1 inhibitory complex by MAIFs leads toactivation of intracellular RhoA, thereby resulting in axonaloutgrowth inhibition, or modulation of cell ... present in the healthy brain, how-ever, they have been found to accumulate in the CNSparenchyma during a wide range of inflammatory insults[20-22] and they are emerging as important players in CNS ... Neuronal injury also results in the presence of dendritic cells (DCs) in the central nervous system, where they can come into contact with myelin debris. The exact mechanisms of interaction of immune...