... all stages of the reaction. The best explanation for these results maybe that the reaction of SDTG at the binding site of onesubunit changes the conformation of the o ther subunit,thereby completely ... (1994) Photo-affinity labelling of the active site of the rat glutathione transferases 3 3 and 1–1 and human glutathione transferase A1–1. Biochem. J. 30 2, 38 3 39 0.24. Katusz,R.M.,Bono,B.&Colman,R.F.(1991)S-(4-Bromo-2 ,3- dioxobutyl)glutathione: ... using the PYMOLsoftware [41].Results and DiscussionSynthesis of SDTGSDTG was synthesized by nucleophile displacement of achlorine atom of the 1 ,3, 5-sym -trichlorotriazine ring by the -SH...