... contexts of homeostasis andinflammation. Therefore, the waning of Treg cells, andensuing breakdown in the self tolerance, could depend on the in situ IL-2 environment. These data all togethersuggest ... individualsubjects.In the implications of such considerations lies the relevance of studies examining defects on a global popu-lation of Treg cells obtained from the peripheral blood,as opposed to examining the ... glycosylation p attern [24]. As such, the pre-sence of a proline rather than a serine at position 6 of the mature IL-2 protein, is associated with a n increasedglycosylation and prolongation of the...