... 1National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892, USA, 2Radiology and Imaging Sciences Program, Clinical Center, National Institutes ... intensity and produce voxel-by-voxelGd concentration maps.Dynamic contrast-enhanced MRI data processing and analysisImaging data was analyzed using the Analysis of Func-tional NeuroImaging (AFNI; ... Fischer344 rats (F344) weighing 190to 200 grams (Harlan Laboratories, Indianapolis, IN) wassecured in a stereotactic frame with ear bars (David KopfInstruments, Tujunga, CA). The right brain caudatenucleus...