... values [22] using the Sequence Detection System Software, and further ana- lyzed in a Spotfire-guided application (Spotfire Decision- Site 8™, TIBCO Software Inc. Somerville, MA) developed within the ... even under in vitro cross-linking and in vivo conditions, a comprehensive assessment of agonistic potential of Ab-01 was undertaken. Methods: In vitro antibody cross-linking and cell culture...
Ngày tải lên: 18/06/2014, 16:20
... simulation hypothesis Over the last decades, promis ing strategies in neuroreh- abilitation, e.g. following cerebral stroke [1-3], have been intro duced based on the so-called simulation hypothesis [4,5]. ... strategies have been introduced over the last decade based on the so- called simulation hypothesis. This hypothesis states that a neural network located in primary and secondary motor ar...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo hóa học: " Motor unit potential morphology differences in individuals with non-specific arm pain and lateral epicondylitis" pptx
... was used to extract needle-detected motor unit potential trains (MUPTs), and needle-detected motor unit potential (MUP) and surface detected motor unit potential (SMUP) morphology and motor unit ... of motor unit action potentials. Muscle Nerve 1989, 12:141-148. 49. Chu J, Takehara I, Li TC, Schwartz I: Skill and selection bias has least influence on motor unit action potential firing rate/fr...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: " On the potential role of glutamate transport in mental fatigue" ppt
... Neurobiol 1989, 33:309-333. 45. Meeks JP, Mennerick S: Selective effects of potassium elevations on glutamate signaling and action potential conduction in hippocampus. J Neurosci 2004, 24:197-206. 46. ... of 9 (page number not for citation purposes) Journal of Neuroinflammation Open Access Hypothesis On the potential role of glutamate transport in mental fatigue Lars Rönnbäck* and Elisabeth H...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học:" Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines" pptx
... not examine the role of EphA receptors in response to dasatinib. EphA2 has been identified as a potential dasatinib sensitivity biomarker [28]. Interestingly EphA2 levels were signifi- cantly ... dasatinib. Identification and valida- tion of appropriate biomarkers will be crucial to maximise the potential clinical benefits of dasatinib treatment for melanoma. Competing interests The authors ....
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Whole blood assessment of antigen specific cellular immune response by real time quantitative PCR: a versatile monitoring and discovery tool" potx
... against infec- tion has not been attempted so far, thus preventing a reli- able assessment of the potential clinical relevance of this technology in a clinical setting. Here we describe a technique ... 57:285-288. 5. Janetzki S, Cox JH, Oden N, Ferrari G: Standardization and vali- dation issues of the ELISPOT assay. Methods Mol Biol 2005, 302:51-86. 6. Janetzki S, Panageas KS, Ben-Porat L, Bo...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Adjuvant therapy of melanoma with interferon: lessons of the past decade" pot
... last few years several important immuno- logical findings have added strong support for this hypothesis that the mechanism of action of IFN is immu- nomodulatory. Moschos et al. [36] reported ... pos- sibility that the Treg cells could influence the clinical out- come of cancer patients has been hypothesized on the basis of their increased number in many cancers [43-48]. Viguier et al. [49] d...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" More insights into the immunosuppressive potential of tumor exosomes" pptx
... function. Nat Rev Immunol 2002, 2:569-579. 24. Gould SJ, Booth AM, Hildreth JE: The Trojan exosome hypothe- sis. Proc Natl Acad Sci USA 2003, 100:10592-10597. 25. Fevrier B, Vilette D, Archer F, Loew ... purposes) Journal of Translational Medicine Open Access Editorial More insights into the immunosuppressive potential of tumor exosomes Veronica Huber 1 , Paola Filipazzi 1 , Manuela Iero 1 ,...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood " pot
... we used Edge software [28], which tests for changes in gene expression over time vs. the null hypothesis that the gene was expressed at a constant level. Among the 518 gene probes that were significantly ... sequence similarity 46, member A FFAR2 (GPR43) 2.7 free fatty acid receptor 2. hCG_1776259 1.9 hypothetical protein FLJ23556 (unknown function) IL1RN 2.1 interleukin 1 receptor antagonist...
Ngày tải lên: 18/06/2014, 15:20