... to inflammation-associated depression [55]. Using mice as a preclinical model, i.p. LPS induces IDO1 activity in the periphery and brain [56] with an increase in central and plasma kynurenine/tryptophan ... ANOVA using StatView (SAS Institute Inc., San Francisco, CA) or SigmaPlot (Systat Software, Inc., San Jose, CA). Where appropriate (social investigation, changes in body weight and food intake), ... London: Academic Press; 2001. 38. Rojo AI, Innamorato NG, Martin-Moreno AM, De Ceballos ML, Yamamoto M, Cuadrado A: Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's...