báo cáo hóa học:" Extending basic principles of measurement models to the design and validation of Patient Reported Outcomes" docx

... drafted the manuscript. BN and DR organ- ized and carried out the original study. MTB performed the statistical analysis. GR and SH designed the study pro- tocol. All authors read and approved the ... nation- ally and internationally [8]. The standard approach of the EuroQol group to establish health preferences is the Vis- ual Analogue Scale rating [9]. The pu...

Ngày tải lên: 18/06/2014, 19:20

... both covalent bonds of FAD to the polypeptide chain of ChitO are required for correct positioning of the flavin to facilitate efficient catalysis. The double anchoring of FAD allows the protein to evolve ... of MAO B. The isoalloxa- zine ring of FAD is in yellow. The axis of the pink helix points directly at the C 2 -O of the isoalloxazine. Cys397, covale...

Ngày tải lên: 16/03/2014, 01:20

... cross-species infections and/ or subsequent virus recombination events have occurred [1]. Therefore, the development of tools for the detection of viruses, the characterization of their genomes and the study of their ... of these anti-sense strand primers). The degeneracy of the primer pools is indicated in parentheses and the highlighted residues are discusse...

Ngày tải lên: 18/06/2014, 22:20

... pole of the patella SPP to the anterior to posterior line extending from the FAAH was 55.5 mm. The mean anterior to posterior distances from the SPP pin, the 2 cm pin, and the 4 cm pin t o the ... artery, the adductor hiatus, the tendinous insertion of the adductor magnus and the femoral artery. Measurements localizing these anatomic structures relative...

Ngày tải lên: 20/06/2014, 04:20

... these phrases, the textual contexts surrounding Chicago and Pickerington are not identical, so to the traditional approach these contexts offer no evidence that Pickerington and Chicago are of ... is not given to the system since the relations (and the types of the arguments) are not known in advance. REALM solves this problem by comparing the dis- tributions of...

Ngày tải lên: 31/03/2014, 01:20

... the protocols, WYF and ZL contributed in the experimental procedures and in the interpretation of the data, SXW, XL, TFL and WBX gave advises on the work and helped in the interpretation of the ... higher incidence of invasion and metastasis at the time of presen- tation to the first biopsy. Therefore, chemotherapy treat- ment is a necessary ancillary met...

Ngày tải lên: 18/06/2014, 15:20

... In the liver, metastatic cancer cells that have survived to the cyto- toxic environment of the microvasculature start to grow in tight association to hepatic sinusoidal endothelial cells and ... Cell Biology and Histology, Bizkaia-48940, Spain and 3 Fernando Vidal-Vanaclocha, Department of Cellular Biology and Histology, School of Medicine and Dentistry, Universit...

Ngày tải lên: 18/06/2014, 15:20

... content and presentation. DJD, ST and BBF provided advice on the conception and design of the clinical and animal experiments. DPS and REWH were imperative to the conception, design and implementation ... respect to the number of genes and the magnitude of gene expression) after 4 hr of stimula- tion, at which point a substantial level of inflammatory...

Ngày tải lên: 18/06/2014, 16:20

... to the maintenance of peripheral tolerance, and their defect leads to organ-specific autoimmune dis- orders such as T1 D. The non-obese diabetic (NOD) mice are a prototypic model of human autoimmunity ... Using this model, the contribution of the IL-2-IL-2R pathway to the development of T1 D and other autoimmune disorders has been extensively studied. In the past...

Ngày tải lên: 18/06/2014, 16:20