... when present, was expressed in > 75 % of the cells, predominantly in the nuclei and in varying intensities, only the intensity of the staining was accounted for and denoted a score from 0 (negative), ... S1. Results Distribution of clinicopathological parameters in the cohort The distribution of patient- and tumour characteristics in the full cohort is...
Ngày tải lên: 20/06/2014, 04:20
... contributor in writing the manuscript while B. C. was a major contributor in writing and in editing the manuscript, as well. C. L. and T.S. analyzed and interpreted the patient data regarding the injury. ... outcome of conservative or minimally operative treatment modal- ities in stability of thumb CMC joint. Inadequate treat- ment may increase the incidence of r...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học: " Can we derive an ''''exchange rate'''' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique" doc
... scores plus interact ions and second-order terms in the case of the SF-36, and on index scores plus s econd-order terms in the case of the NIHSS and Barthel algo rith ms. For all algorithms, we retained ... participated in the design of the study and inter- pretation of results, and suggested edits and revisions to the manuscript. JS contributed to the...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo hóa học: " Motavizumab, A Neutralizing Anti-Respiratory Syncytial Virus (Rsv) Monoclonal Antibody Significantly Modifies The Local And Systemic Cytokine Responses Induced By Rsv In The Mouse Model" potx
... below the level of detection of the assay in the non-infected control group, and the objective of the study was to evaluate the effect of motavizumab in the inflammatory response induced by RSV, the ... main viral respira- tory pathogen causing hospitalization in infants and young children worldwide[1]. It infects nearly 70% of infants in their first ye...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " Herpes simplex virus type-1(HSV-1) oncolytic and highly fusogenic mutants carrying the NV1020 genomic deletion effectively inhibit primary and metastatic tumors in mice" pptx
... by diagnostic PCR and DNA sequenc- ing to ensure the stability of the viral genomes, the presence of the parental Onc deletions and the presence of the gKsyn1 mutation within the gK gene, as described ... derived from human laryngeal carcinoma [38]. Therefore, to further increase the ability of the OncSyn virus to fuse all types of cells, we generated the O...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" A general method for nested RT-PCR amplification and sequencing the complete HCV genotype 1 open reading frame" pdf
... the ORF at both the nucleotide and the amino acid level, especially in hypervariable regions (HVR1 and HVR2) within the E2 region [7,8]. Analysis of the NS5B region encoding the viral RNA polymerase ... prevent HCV infection. The best avail- able therapy for HCV infection is a combination of pegylated interferon α and ribavirin, an oral guanosine analogue [4]. The...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo hóa học: " cDNA targets improve whole blood gene expression profiling and enhance detection of pharmocodynamic biomarkers: a quantitative platform analysis" ppt
... contributed to the study design, participated in the expression profiling assays and participated in the ex vivo dosing study. DA participated in the expression profiling assays and participated in the ... with the data analysis and participated in drafting and editing of the manuscript. SL completed the analysis of the protocol selection study, partici...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Differential aquaporin 4 expression during edema build-up and resolution phases of brain inflammation" doc
... in the evolution of interstitial edema a nd could be a ssociated wi th the worsening of a patient’ s condition. Following injury, a delay in effi- cient upregulation of AQP4 could result in the ... phase of edema, as low AQP4 expression may be insufficient to counteract the opening of the BBB . On the other hand, the pronoun ced but delayed upregula- tion of AQ...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo hóa học: " Rift Valley fever virus structural proteins: expression, characterization and assembly of recombinant proteins" potx
... expression of RVFV Gn and Gc proteins in insect cells resulted in detection of both proteins on the surface of the non-permeabilized infected cells. The presence of Gn and Gc on the surface of infected ... suggesting that N was the major component in those fractions. To confirm further that the eluted band was indeed the N protein of RVFV, and had the s...
Ngày tải lên: 20/06/2014, 01:20