báo cáo hóa học:" Evaluating change in health-related quality of life in adult rhinitis: Responsiveness of the Rhinosinusitis Disability Index" potx
báo cáo hóa học:" Evaluating change in health-related quality of life in adult rhinitis: Responsiveness of the Rhinosinusitis Disability Index" potx
... purposes)Health and Quality of Life OutcomesOpen AccessResearch Evaluating change in health-related quality of life in adult rhinitis: Responsiveness of the Rhinosinusitis Disability IndexHubert ... Corresponding author AbstractBackground: The Rhinosinusitis Disability Index (RSDI) is a validated measure of health-related quality of life (HRQL) in rhinitis. Responsiveness of the RSDI to changes ... status Change in the RSDI at the individual level correlatedmoderately well with changes in the RSS-4, SF-12 PCS,CES-D, and PCRQ. Moreover, changes were in the antici- Change in health-related quality...
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báo cáo hóa học: " Evaluating oral health-related quality of life measure for children and preadolescents with temporomandibular disorder" pptx
... variable pain, which was the sum of the positive responses to question number 3 of the RDC/TMD Axis II, “Have you had pain in the face, jaw,temple, in front of the ear or in the ear in the pastmonth?” ... to the elimination of indistinct or temporaryclicking sounds [32], decreasing the probability of falsepositive results. In TMD groups, the presence of headaches was higher in children than in ... underpinnings of any scientific measure. The reliability of a diagnosticinstrument sets the upper limit for its validity [42]. Sev-eral studies evaluating the reliability of clinical findingshave...
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Báo cáo hóa học: "Epigenetic change in E-Cardherin and COX-2 to predict chronic periodontitis" pptx
... with grinding. 20 μlofProteinaseK(10 mg/ml) was added to the sample mixture and mixedbyvortexing.Thesamplewaslysedbyincubationat60°C for 30 minutes, and the tube was inverted every5 minutes. ... on clinical inspection via probing depths,attachment levels, bleeding, plaque index and the use of x-rays or other radiographic methods [24]. The oral cav-ity of the patient is usually initially ... linked to a variety of conditions,including tumorigenesis, chronic inflammation, andintestinal metaplasia [3].There are many key indicators of cancer, of which twoare significant to this investigation:...
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Báo cáo hóa học: " Evaluating interaction forces between BSA and rabbit anti-BSA in sulphathiazole sodium, tylosin and levofloxacin solution by AFM" potx
... anti-BSA. These findings may enhance ourunderstanding of antigen/antibody binding processes in the presence of drug molecules, and hence indicate thatAFM could be helpful in the design and screening ... screening of drugs-modulating protein-protein interaction processes.1. IntroductionA molecular level understanding of protein-protein inter-actions is fundamentall y important in the life sciences. ... antigen/antibody bindingprocesses in the presence o f drug molecules, and henceindicate the AFM could be helpful in the design andscreening of drugs modulating protein-protein interac-tion processes.AcknowledgementsThis...
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báo cáo hóa học:" Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer" pdf
... Analysis The preprocessing of data that included averaging of tech-nical repeats, interpolation of missing or non-alignedpoints, binning of neighboring points to reduce data com-plexity, removal of ... reflect the low resolu-tion of the analyzer operating in the linear mode or mightresult in overlapping of ions originating from protein/peptides of very similar molecular masses. In addition,because ... further characterize the quality of classification, receiveroperating curves (ROC) were computed by changing the value of the classification threshold in the SVM classifiers,and averaging the...
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Báo cáo hóa học: " Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab" doc
... not Cetuximab alone.However the increase of RR due to Cetuximab addic-tion in CPT-11 containing regimens in first or second line of therapy is in the same range. In the Crystal trial RR was59.3% ... reasonable toanalyse patients in first or more line of chemotherapytogether. The role of increased EGFR-GCN and of number of chemotherapy lines as prognostic factors in the Kaplan-Meier curves for ... by the same increase of chromosome 7 on which the EGFR gene is located.Therefore, much of the data from literature is similaralthough an international consensus on the definition of cut-off...
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Báo cáo hóa học: " Melanoma: A model for testing new agents in combination therapies" doc
... convincing proof of principle that some of these novel approaches constitutenew tools for the treatment of cancer, they have alsoproven that a single drug is unlikely to induce lasting clin-ical ... by RNA screening [50]. Another appealing con-cept takes advantage of the intrinsic vulnerability of atumor; for example, combining a DNA repair inhibitor of PARP with a DNA damaging agent may ... vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): a trial coordinated by the...
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Báo cáo hóa học: " Adenoviruses with an avb integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal cancer metastases" pdf
... viralpreparations.Targeting viruses to cell surface avb integrins byinserting RGD tripeptide motif into the HI loop of the fiber knob (Ad5lucRGD) or into the fiber shaft KKTKdomain (AdTLRGDK) increased the expression ... JuseliusFoundation, Academy of Finland, Biocentrum Helsinki. Akseli Hemminki is K.Albin Johansson Research Professor of the Foundation for the FinnishCancer Institute. Authors declare no conflict of interest.Author ... irus,increased tumor cell transduction is achieved with ade-noviruses with RGD moieties in the HI loop of the fiberor in the KKTK domain of the fiber [30]. Furthermore,mutation of the KKTK...
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Báo cáo hóa học: " MMP-1 is a (pre-)invasive factor in Barrettassociated esophageal adenocarcinomas and is associated with positive lymph node status" doc
... Bovine Serum, 100 units/ml of penicillin and100 μg/ml of streptomycin. Cytospins of the OE-33 cellline were fixed in acetone and dried for 10 minutes.Rehydration, blo cking, and the staining ... thus sustain m ulti-step carcinogenesis and f urthertumor growth. These findings may contribute to the further understanding of the patho genesis of esophagealcarcinogenesis. Furthermore, MMP-1 ... Immunohistochemical staining of MMP-1 from the OE-33 adenocarcinoma cancer cell line and MMP-1 gene expression in human BE and EAC. MMP-1 staining in cytospins from the OE-33 adenocarcinoma cancer cell line served...
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Báo cáo hóa học: "Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque" ppt
... concentrations of NSC23766 would be needed toinhibit Rac1 in platelets in blood considering the possi-blebindingofthedrugtoplasmaproteinsandotherblood cells and its crossing of the cell membrane ... surfacefields of the size of 237900 μm2(located in the middle of the channels of the viewing window) were recorded,and fluorescence images were later analyzed off-stage byquantifying the area ... inhibition of sti-mulus-induced platelet aggregation in blood was foundto be in the sam e range as the IC50 of NSC23766 in the in vitro re constitution system consisting only of the twoproteins...
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