... testing in compliance with eu Pharmacopoeia 2.6.1 (sterility) and the validation of the potency assay in an ATMP that is constituted of bone- marrow mononucle- ated cells used in cardiac regeneration. Materials ... types of potency assays can be envisioned: in vitro assays using cell systems and in vivo assays using animal models. As concerning...
Ngày tải lên: 18/06/2014, 15:20
... augments H. pylori- induced cell death and DNA fragmentation in gastric epithelial cells To investigate the relations of PAR-2 expression, cell death, and DNA fragmentation, cells were transfected with ... the role of PAR-2 on H. pylori-induced cell death was investigated by determining cell viability, DNA fragmentation, and the activation of MAPK...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc
... 32:468-478. doi:10.1186/1479-5876-8-113 Cite this article as: d’Hennezel et al.: IL-2 as a therapeutic target for the restoration of Foxp3 + regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and ... facilitate hematopoietic stem cell trans- plantation (HSCT). Studies in such patients indicate that Treg cells d...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignancies" doc
... is a longer-acting form of G-CSF, whose effects on dendritic cell (DC) and regulatory T cell (Treg) mobilization, and on the in vivo and ex vivo release of immune modulating cytokines remain unexplored. Methods: ... RESEA R C H Open Access Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignanc...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: "The impact of regular physical activity on fatigue, depression and quality of life in persons with multiple sclerosis" pot
... of 10 (page number not for citation purposes) Health and Quality of Life Outcomes Open Access Research The impact of regular physical activity on fatigue, depression and quality of life in persons ... the Physical Function, Bodily Pain and Physical Component Summary Score of the SF36 (Figures 4, 5 and 6). The influence of the quantity of re...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Testing a model of association between patient identified problems and responses to global measures of health in low back pain patients: a prospective study" pdf
... association between patient identified functional problems and responses to global measures of health in low back pain patients. Methods: Participants in a low back pain clinical trial were followed ... Access Research Testing a model of association between patient identified problems and responses to global measures of...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Impact of gastroesophageal reflux disease on work absenteeism, presenteeism and productivity in daily life: a European observational study" doc
... employee of AstraZeneca. Authors' contributions All authors were involved in data interpretation and man- uscript preparation. Data analysis was provided by Astra- Zeneca. All authors read and approved ... Agréus L, Jab- lonowski H, Tafalla M: Consultation rates and characteristics of gastroesophageal reflux disease in primary care: a European observational stud...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Initial validation of the Argentinean Spanish version of the PedsQL™ 4.0 Generic Core Scales in children and adolescents with chronic diseases: acceptability and comprehensibility in low-income settings" pdf
... Quality of Life Outcomes Open Access Research Initial validation of the Argentinean Spanish version of the PedsQL™ 4.0 Generic Core Scales in children and adolescents with chronic diseases: acceptability ... the Argentinean Spanish Validation of PedsQL™ 4.0 in children with chronic conditionsFigure 2 Flowchart and Patient D...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Change in patient concerns following total knee arthroplasty described with the International Classification of Functioning, Disability and Health: a repeated measures design" docx
... Outcomes Open Access Research Change in patient concerns following total knee arthroplasty described with the International Classification of Functioning, Disability and Health: a repeated measures ... contributions RR, AMD and BMC designed the study. RR collected and analyzed the data and drafted the manuscript with regular feedback fro...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo hóa học: " Effects of muscle fatigue on gait characteristics under single and dual-task conditions in young and older adults" ppt
... objectives of this study were to examine the effects of muscle fatigue on gait characteristics under single and dual-task conditions in young and older adults and to determine the impact of muscle fatigue ... Granacher et al.: Effects of muscle fatigue on gait characteristics under single and dual-task conditions in young...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: " Production of IL-16 correlates with CD4+ Th1 inflammation and phosphorylation of axonal cytoskeleton in multiple sclerosis lesions" pptx
... regulation of CD4 +Th1 inflammation, and inflammation- induced changes in axonal cytoskele- ton in lesions sampled from 39 autopsies of patients with MS and 19 controls. We found marked increases in IL-16 and ... Central Page 1 of 13 (page number not for citation purposes) Journal of Neuroinflammation Open Access Research Production of IL-16 correlates wi...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo hóa học: " Differential expression of papillomavirus L1 proteins encoded by authentic and codon modified L1 genes in methylcellulose-treated mouse keratinocytes" pptx
... Access Short report Differential expression of papillomavirus L1 proteins encoded by authentic and codon modified L1 genes in methylcellulose-treated mouse keratinocytes Xiao Wang, Bo Li and Kong-Nan ... methylcellulose to induce cell differentiation of primary mouse keratinocytes (KCs) in in vitro culture and assessed the expression of authent...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " Differential inhibition of human cytomegalovirus (HCMV) by toll-like receptor ligands mediated by interferon-beta in human foreskin fibroblasts and cervical tissue" pdf
... Central Page 1 of 10 (page number not for citation purposes) Virology Journal Open Access Research Differential inhibition of human cytomegalovirus (HCMV) by toll-like receptor ligands mediated by interferon-beta ... stim- IL-8 secretion and HCMV inhibition in HFF induced by TLR ligandsFigure 1 IL-8 secretion and HCMV inhibition in HFF induced by...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters" potx
... unreported genetic instability was observed, resulting in a higher fre- quency of point mutations and random insertions of U nucleotides in poly-U tracts of the rhMPV/ M2-2 genomic RNA. Results Expression of M2-2 ... insertions and point mutations in rhMPV/ M2-2 compared to rhMPVFigure 3 Chromatogram and frequency of A insertions and point mutations in rhMPV/ M...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" Change in condom and other barrier method use during and after an HIV prevention trial in Zimbabwe" potx
... 11 RESEARC H Open Access Change in condom and other barrier method use during and after an HIV prevention trial in Zimbabwe Ariane van der Straten 1,2* , Helen Cheng 1 , Alexandra M Minnis 1,3 Abstract Background: ... enrolment, final MIRA and post -trial visits. We used multivariable random effects logistic regression to examine changes in method use...
Ngày tải lên: 20/06/2014, 08:20