... pigs also have similar cardiac anatomy and physiol-ogy as humans [16]. The endotoxin infusion modelappeared to provide a highly stable and predictable circu-latory and pathophysiological state ... porcine endotoxemia. Shock 2003, 19(6):526-532.22. Kondo A, Saito Y, Seki A, Sugiura C, Maegaki Y, Nakayama Y, Yagi K,Ohno K: Delayed neuropsychiatric syndrome in a child fol-lowing carbon monoxide ... study conducted in endotoxin administered pigs, as evaluated by measuredconcentrations of plasma cytokines (TNF-alpha, IL-6, IL-1beta and IL-10). The model was characterised by massiveinflammation...