... for evalua- tion of dasatinib in clinical trials in melanoma patients. Two clinical trials of dasatinib in melanoma are currently underway, including a phase I/II study of dasatinib in combination ... cell cycle arrest, apoptosis, migration and invasion in human melanoma cell lines. Expression and activation of Src kinase, FAK and EphA2 were also examined in...
Ngày tải lên: 18/06/2014, 15:20
... Translational Medicine Open Access Research Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first ... relapsed by the end of treatment. Changes in Global Gene Expression Gene expression in PBMC changed dramatically and rap- idly during PEG-in...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Emerging concepts in biomarker discovery; The US-Japan workshop on immunological molecular markers in oncology" pot
... for citation purposes) Journal of Translational Medicine Open Access Commentary Emerging concepts in biomarker discovery; The US-Japan workshop on immunological molecular markers in oncology Hideaki ... participate in the workshop including the National Cancer Institute (NCI), the National Institutes of Health (NIH) Center for Human Immunology (CHI) and th...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" The "Excellence in Translational Medicine" and "Bedside-to-Bench" Awards 2007–08" doc
... tumour-associated antigens and thereby, represent a major obstacle to immunotherapy. Thus, reducing their number or inhibiting their effector functions intuitively has the potential of increasing the efficacy ... and man toward delineating, e.g., the relative effects of T cells and depletion of Tregs. In the process, the paper by Rasku et al. [5] exemplifies the jour- ney...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Evolutionary concepts in biobanking - the BC BioLibrary" docx
... streamline and improve biobanking activities; 4) the BC BioLibrary enhances qual- ity and accessibility of biospecimens; and 5) the BC BioLi- brary contributes to the sustainability of biobanking in ... data capture rel- evant to the BCU, the BCU inventory database ('BCU Cat- alogue'), as well as a web based training curriculum. The evolution from this single,...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "Genomic aberrations in borderline ovarian tumors" doc
... tumor calculated in the present series was 18.72. It is interest- ing to note that for the bilateral borderline ovarian tumors the ANCA index was 24.5 whereas for the uni- lateral borderline ovarian tumors ... rominently in both overt carcinomas [37,50] and in the present series (the gains were found in 5 of 5 cases with bilateral borderl ine tumors and in 4 of 6 informative...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic " ppt
... Alvarez 1 Abstract Background: Angiotensin and serotonin have been identified as inducers of cardiac hypertrophy. DNA polymorphisms at the genes encoding components of the angiotensin and serotonin systems have been ... et al., Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic cardiomyopath...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Heart rate in professional musicians" pot
... belonging to the main clarinetist of a symphonic orchestra during the REHEARSAL (in black ink) and the CONCERT (pink line) of the same musical pieceFigure 3 Overlapped printouts belonging to ... daily working schedule. His purpose was to tailor treatments for optimal protection in patients with coronary artery diseases, taking into account the timing of occupational- induced changes in...
Ngày tải lên: 20/06/2014, 00:20
báo cáo hóa học:" Does metformin affect ovarian morphology in patients with polycystic ovary syndrome? A retrospective cross-sectional preliminary analysis" pot
... 5 (page number not for citation purposes) Journal of Ovarian Research Open Access Research Does metformin affect ovarian morphology in patients with polycystic ovary syndrome? A retrospective cross-sectional ... hyperinsulinemia and insulin resistance due to the administration of a largely used insulin sensitizing agent, such as metformin, and modification in...
Ngày tải lên: 20/06/2014, 07:20
báo cáo hóa học:" CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion" pdf
... CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-depen- dent and FAK-independent fashion Journal of Ovarian Research 2010, 3:15 Received: ... and reproduction in any medium, provided the original work is properly cited. Research CCR9 interactions support ovarian cancer cell surviva...
Ngày tải lên: 20/06/2014, 07:20
báo cáo hóa học:" Predictive value of ovarian stroma measurement for cardiovascular risk in polycyctic ovary syndrome: a case control study" pptx
... (Table 3). Analysis of the ultrasound appearance of the ovaries showed that PCOS patients showed had a higher ovarian and stromal volume, stromal area and a higher area stromal area/area ovary ... 41:131-4. doi:10.1186/1757-2215-3-25 Cite this article as: Loverro et al.: Predictive value of ovarian stroma measurement for cardiovascular risk in polycyctic ova...
Ngày tải lên: 20/06/2014, 07:20
báo cáo hóa học:" Metformin therapy in a hyperandrogenic anovulatory mutant murine model with polycystic ovarian syndrome characteristics improves oocyte maturity during superovulation" pot
... article as: Sabatini et al.: Metformin therapy in a hyperandrogenic anovulatory mutant murine model with polycystic ovarian syndrome characteristics improves oocyte maturity during superovulation. ... hyperandrogenic anovulatory mutant murine model with polycystic ovarian syndrome characteristics improves oocyte maturity during s...
Ngày tải lên: 20/06/2014, 07:20
báo cáo hóa học:" HOX genes in ovarian cancer" pot
... suggesting b1integrinhasaroleinmediating these changes. Intriguingly, these changes in protein level are not reflected at the RNA level, indicating that the effect of HOXA4 on b1 integrin and ... [17-20]. Function of HOX genes in ovarian cancer Tumour Growth In addition to phenotypic determination, HOX genes are thought to play a role in the oncogenesis of ovarian can- cer...
Ngày tải lên: 20/06/2014, 08:20
Báo cáo hóa học: " Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment" pptx
... (H31 0A) antibody of diff erent tissue specimens.At×40 magnification, (a) human pancreas cancer with strong staining, (b) human pancreas cancer with moderate staining, (c) human pancreas cancer with ... ORIGINAL RESEARCH Open Access Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment Mark D Girgis 1,3 , Tove Olafsen 2...
Ngày tải lên: 20/06/2014, 22:20
báo cáo hóa học: " Topological confinement in an antisymmetric potential in bilayer graphene in the presence of a magnetic field" pptx
... states in a kink potential profile under a per- pendicular external magnetic field, both for the case of a single potential kink, as well as fo r a kink-antikink pair. One advantage of such a setup ... 6:452 http://www.nanoscalereslett.com/content/6/1/452 Page 6 of 10 NANO EXPRESS Open Access Topological confinement in an antisymmetric potential in bil...
Ngày tải lên: 21/06/2014, 02:20