báo cáo hóa học:" On the path to translation: Highlights from the 2010 Canadian Conference on Ovarian Cancer Research" pot
báo cáo hóa học:" KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells" potx
... direct action on mitochondrial membranes [19], second, by inducingmitochondrial depolarization through Bid [20], andthird, by direct activation on effector caspases [21]. To fur-ther characterize ... suggests the impor-tance of identifying the molecular phenotype of the tumorprior to the initiation of therapy.ConclusionAdministration of Paclitaxel to patients with high percent-age Type I cancer ... caspase-2 activa-tion leads to the direct activation of effector caspases with-out the involvement of the mitochondria.ARRY-520 does not induce NF-κB activation and cytokine secretion in Type I...
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báo cáo hóa học:" A systematic approach to biomarker discovery; Preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers"" docx
... ofsamples to achieve the same statistical power according to the variance expected in the study population and itsresponsiveness to therapy and/or susceptibility to toxicside effects (i.e. the expected ... comparisons will be a focusof discussion. Furthermore, the definition used for the collection of clinical information or metadata derived from the bedside vary widely and are likely to make the task ... transcriptional analy-sis to the electroencephalographic responses to stimulation which inform about the reaction to stimulus;thus, while mRNA provides information about the "brainresponse"...
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báo cáo hóa học: " Evaluation of adaptation to visually induced motion sickness based on the maximum cross-correlation between pulse transmission time and heart rate" docx
... thisphenomenon represents an adaptation to VIMS derived from the repetitive exposure to the same swaying videoimage. On the other hand, TS of the 5 subjects on Day 3 werehigher than on Day 1 such ... VIMS. On the other hand, an important feature of motion sick-ness is the adaptation process. Adaptation occurs withrepetitive exposure to the motion that causes the motionsickness [8,9]. The ... objectively evaluated the effects of the repetitive exposures to these stimuli on humans. The purpose of this study is to investigate the adaptation to visually induced motion sickness by physiological...
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báo cáo hóa học:" Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis" docx
... ICAM-1. In the liver, metastatic cancer cells that have survived to the cyto-toxic environment of the microvasculature start to grow intight association to hepatic sinusoidal endothelial cellsand ... incubated on 0.01% type I collagen-coated inserts with 8 μm-pores and placed on top of 2 cm2wells (Becton Dickinson, Madrid, Spain) containingRPMI or conditioned media from either monolayer-or3D-cultured ... promoteAngiogenic potential of cancer cells from monolayer and 3D-cultured CT26 cancer cellsFigure 4Angiogenic potential of cancer cells from monolayer and 3D-cultured CT26 cancer cells. One 3D-spheroid...
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Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc
... contexts of homeostasis andinflammation. Therefore, the waning of Treg cells, andensuing breakdown in the self tolerance, could depend on the in situ IL-2 environment. These data all togethersuggest ... stabilit y and their responsiveness to the IL-2 can be controlled by different miRNA there-fore opening new avenues for potential therapeutic tar-gets for the prevention and treatment of autoimmunedisorders.IL-2 ... D. Using this model, the contribution of the IL-2-IL-2R pathway to the development of T1 D and other autoimmune disorders has been extensively studied. In the past years, stronggenetic and molecular...
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báo cáo hóa học: " An exploratory study to evaluate the utility of an adapted Mother Generated Index (MGI) in assessment of postpartum quality of life in India" potx
... for the Mother Generated Index evaluationbut 43 women from LSEC, 7 women from the MSEC and4 women from HSEC could not be administered the ques-tionnaire. The reasons included refusal of consent, ... as a preparatory step prior to the survey.These involved asking the mothers to identify the mostimportant positive and negative areas of their lives and to rate their importance in the post partum ... translated intoEnglish to allow administration in either language. The QOL section included three related parts. One included the Mother Generated Index (see additional file 1), the second included...
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báo cáo hóa học: " Using animal models to determine the significance of complement activation in Alzheimer''''s disease" pptx
... admin-istration of the excitotoxin kainic acid [108,109], orinjection of the neurotoxin colchicine into the dorsal hip-pocampus [109]. Surgical transection of the perforantpathway increased ... Though the acute neuronal damagein these studies differs from the chronic, progressive neu-rodegenerative process that occurs in AD, these resultsdemonstrated that the neuronal response to injuryincludes ... [52], and the increased neuronal loss in the APP/sCrry mouse may bedue to decreased production of C3a as well as the opsonin, C3b. However, whether inhibition of comple-ment activation in the AD...
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Tài liệu Báo cáo khoa học: An immunomodulator used to protect young in the pouch of the Tammar wallaby, Macropus eugenii pptx
... below 100 lgÆmL)1, and with the excep-tion of one component, they have not been studied fur-ther. The exception is the only peptide identified (byMS ⁄ MS data) from the pouch swabs. This peptide ... lactation period [19–25]; generally the pro-tein content varies significantly from the early to the late lactation period.Female wallabies produce a waxy secretion in the pouch, and the constituency ... via one or both CCK receptorsubtypes. In the guinea pig ileum, CCK receptor agon-ists act to cause contraction of smooth muscle [33].CCK1receptors are present on the smooth muscle, andcontract...
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Tài liệu Báo cáo khoa học: "Using adaptor grammars to identify synergies in the unsupervised acquisition of linguistic structure" docx
... distribution from DP(α, H) by repeatedly drawinga ball at random from the urn and then returning itplus an additional ball of the same color to the urn.In an adaptor grammar there is one DP for ... Figure 7, Consonant expands to any consonantand Vowel expands to any vowel. This gram-mar defines a Word to consist of up to three Syl-lables, where each Syllable consists of an Onsetand a ... distri-bution H and a concentration parameter α, and itreturns a distribution over distributions DP(α, H).There are several different ways to define DPs; oneof the most useful is the characterization...
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Báo cáo khoa học: Mercury(II) binding to metallothioneins Variables governing the formation and structural features of the mammalian Hg-MT species pptx
... by the comparison of the CDspectra of isostoichiometric species obtained under differentconditions. The contribution of the counter-ion to the 3Dstructure of the Hg-MT aggregates is demonstrated ... does not depend on the nature of the counter-ion. Conversely, the stabilizationtime determines the Hg-bMTstoichiometryofmostofthespecies formed and becomes particularly evident as the Scheme 3. ... Universitat Auto`noma de Barcelona, SpainWith the a im of extending our knowledge on the reactionpathways of Zn-metallothionein (M T) and apo-MT speciesin the presence of Hg(II), we monitored the...
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Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Báo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíChuong 2 nhận dạng rui roKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ