báo cáo hóa học:" Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)" pptx
báo cáo hóa học:" Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients" potx
... (IGF1R): Insulin-like Growth Factor-1 receptor; (IGFBP-3): Insulin-like Growth Factor Binding Protein-3; (IGFBP-4): Insulin-like Growth Factor Binding; Protein-4; (MAPK): Mitogen-activated protein kinase; ... Com- bination therapy of insulin-like growth factor binding pro- tein-3 and retinoid X receptor ligands synergize on prostate cancer cell apoptosis in vitro and in vivo. Clin...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Drugs targeting the mitochondrial pore act as citotoxic and cytostatic agents in temozolomide-resistant glioma cells" pptx
... cells in 96 well plates. The following day cells were stained for 10 minutes in medium containing JC-1 at the final concentration of 50 μg/ml. After removal of JC-1, a new medium containing the ... J, Wejksza K, Zdzisiñska B and Kandefer-Szerszeñ M: Betulinic acid decreases expression of bcl-2 and cyclin D1, inhibits proliferation, migration and induces apoptosis in cancer cel...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx
... epithelial survival in the setting of stress. Understanding the molecular structure and function of it and its ligands in the setting of inflammation is critically important in understanding the role ... results in chronic inflammation and in many instances is the setting in which epithelial malignancies arise. RAGE and its isoforms sit in a pivotal role, regulating meta...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Is there a relationship between factor V Leiden and type 2 diabetes?" doc
... multivariate gene- gene interaction and gene-enviromental interaction. Conclusion So, our data pointed out again an interesting aspect of the linking between FVL gene variant, diabetes and athero- Table ... although this increase did not raise statistical significance. Discussion: our data pointed out an interesting aspect of the linking between FVL gene variant, diabetes and atherothro...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways" ppt
... platelets and interacts with integrins and FINC in order to maintain cellular integrity (Figure 8) [180]. Enhanced production of VWF is also indicative of vascular injury, thrombus formation, inflammation ... the RGD domains are present in numerous integral plasma membrane proteins identified in this study including integrin and other cell adhesion proteins [82]. In addition, th...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899" pot
... estra- mustine, mitoxantrone, and vinorelbine in patients with CRPC. One study demonstrated a potential clinical ben- efit to adding estramustine with vinorelbine as second line therapy in CRPC ... receptor tyrosine kinase inhibitor ZD1839 in non-small cell lung cancer and other solid tumors. Clin. Cancer Res., 9: 2040-2048, 2003. Clin Cancer Res 2003, 9:1990-1994. 16. Jaeschk...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " cDNA targets improve whole blood gene expression profiling and enhance detection of pharmocodynamic biomarkers: a quantitative platform analysis" ppt
... the high and variable concentrations of globin transcripts in whole blood total RNA potentially resulting in non-specific probe binding and high background. In this study, we investigated and quantified ... study, participated in the analysis of the SAHA data and participated in the drafting and editing of the manuscript. All authors read and approved the final manuscrip...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Can we derive an ''''exchange rate'''' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique" doc
... Ware J: Using generic measures of functional health and well- being to increase understanding of disease burden. Spine 2000, 25:1467. 17. Ware J, Kosinski M and Keller S: SF-36 physical and mental hea ... improvements in predictive validity that we were able to obtain by deriving separate transformations for clinically distinct subgroups of patients. Finally, our findings suggest that...
Ngày tải lên: 18/06/2014, 18:20
báo cáo hóa học: " Measuring the ICF components of impairment, activity limitation and participation restriction: an item analysis using classical test theory and item response theory" potx
... participated in the conception and design of the study, the analysis and the drafting and revision of the manu- script. MJ participated in the conception and design of the study and the drafting and revision ... your joint in bed at night? OXFORD 3.68 1.21 I7. How severe is your stiffness after first wakening in the morning? WOMAC 3.39 0.88 I8. How severe is your stiffne...
Ngày tải lên: 18/06/2014, 18:20
báo cáo hóa học: " The minimal important difference of the hospital anxiety and depression scale in patients with chronic obstructive pulmonary disease" pot
... the self-administered and validated German version of the HADS[19] The HADS measures depression and generalised anxiety in in- and outpatients and in community settings. It contains 14 statements describing ... approximately 1.5 points in COPD patients. Investigators and those interpreting clinical research can use this minimal important difference to determine whether treatme...
Ngày tải lên: 18/06/2014, 19:20