... curves, the cutoff score for p300 high expression was defined when more than 60% of the tumor cells were positively stained. High expression of p300 was examined in 60/123 (48.8%) of HCCs and in 8/123 ... participates in the regulation of a wide range of cell biological processes and mutation of p300 has been identified in certain types of human cancers. However,...
Ngày tải lên: 18/06/2014, 16:20
... Molecu- lar cloning and cold-inducible gene expression of ferritin H subunit isoforms in rainbow trout cells. J Biol Chem 271, 26908–26913. 13 Tang SJ, Sun KH, Sun GH, Lin G, Lin WW & Chuang MJ ... protein. 1v6a.pdb des- cribes secondary, tertiary and quaternary structures of LDH-A from the skeletal muscle of common carp including subunit and ligand interactions. Therefore...
Ngày tải lên: 19/02/2014, 02:20
Báo cáo khoa học: Differential expression of endogenous sialidases of human monocytes during cellular differentiation into macrophages potx
... threshold in the log-linear range of RT-PCR, indicating the relative amount of starting template in each sample. The fold change in expression of Neu1, Neu3, and Neu4 RNAs in macrophages compared ... associated with increased expression of RNA encoding Neu1, Neu2, Neu3, and Neu4, the relative amount of these RNAs in freshly isolated monocytes and in macrophages...
Ngày tải lên: 16/03/2014, 19:20
Báo cáo khoa học: Differential expression of liver and kidney proteins in a mouse model for primary hyperoxaluria type I pdf
... overexpression of enolase 1 and malic enzyme 1 supports the induction of fatty acid metabolism. The reduction in d-amino acid oxi- dase 1 expression in the kidney proteome is interesting, in view ... equilibrated for 15 min in reducing buffer contain- ing 50 mm Tris ⁄ HCl, pH 8.8, 30% glycerol, 6 m urea, 2% SDS and 1% dithiothreitol, followed by a blocking step in similar...
Ngày tải lên: 23/03/2014, 03:20
Báo cáo hóa học: " Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032" potx
... functioning as specific inhibitors of the BRAF V600E mutated kinase with a favorable profile compared to wild type kinases [9,22]. Understanding the patterns of sensitivity and resistance in melanomas ... particular inter- est in looking at this pathway. The genomic analysis revealed that alterations in PI3K/Akt, including deletions of PTEN, amplifications of AKT and activa...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo sinh học: " Differential expression of papillomavirus L1 proteins encoded by authentic and codon modified L1 genes in methylcellulose-treated mouse keratinocytes" ppt
... change expression patterns of the other KC differentia- tion markers by reducing expression of basal keratins K14 and increasing expression of keratins K1 and K10 (data not shown). These data indicate ... respectively transfected with 2 μg of each of the four PV L1 plasmid Cell morphology and expression of involucrin in the primary mouse KCs grown in KC-SF medium...
Ngày tải lên: 18/06/2014, 18:20
báo cáo hóa học: " Differential regulation of Aβ42-induced neuronal C1q synthesis and microglial activation" pptx
... synthesis and microglial activation Rong Fan and Andrea J Tenner* Address: Department of Molecular Biology and Biochemistry, Institute of Brain Aging and Dementia, University of California, Irvine, ... receptors are involved in Aβ injury and signaling in neurons. Some lead to neuronal C1q induction, whereas other(s) lead to intraneuronal accumulation of Aβ and/ or stim...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo khoa học: Recombinant expression of an insulin-like peptide 3 (INSL3) precursor and its enzymatic conversion to mature human INSL3 pot
... in humans, including insulin, insulin- like growth factor-1 and -2, relaxin-1, -2 and -3, and INSL4, -5 and -6. INSL3 was cloned in the early 1990s from the cDNA library of the Leydig cells of the ... spectra of the human INSL3 precursor before and after in vitro refolding. (B) Far-UV spec- tra of the mature human INSL3 and porcine insulin. Fig. 7. cAMP activity of...
Ngày tải lên: 30/03/2014, 01:20
báo cáo hóa học: " Measurement properties of the Dizziness Handicap Inventory by cross-sectional and longitudinal designs" docx
... DHI is intended to measure the handicapping effects of dizziness on physical, emotional and functional sub- domains [1]. To examine validity and responsiveness of the DHI-N, the following condition ... scores of the DHI-N and the VSS-sf-N indicated similar con- structs; a reduction in perceived handicapping effect of dizziness was associated with a reduction in perceived fre...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo sinh học: " Constitutive expression of Atlantic salmon Mx1 protein in CHSE-214 cells confers resistance to Infectious Salmon Anaemia virus" ppt
... susceptibility of fish at an early age, and insuffi- cient knowledge of pathogenesis of virus infections. In this context, we are studying the mechanisms by which ISAV interacts with its host, including ... IFN-sys- tem of Atlantic salmon. Thus, we were interested in ana- lyzing ISAV strains having phenotypically different growth properties in the CHSE-214 cell line to gain fu...
Ngày tải lên: 19/06/2014, 08:20