... (pro-uPA). uPA activate plasminogen a serine pro- tease that can digest ECM proteins and activate MMPs, a family of proteolytic enzymes that are also major partici- pants in ECM degradation and cancer ... 8 RESEARCH Open Access Cathepsin B: a potential prognostic marker for inflammatory breast cancer Mohamed A Nouh 1† , Mona M Mohamed 2*† , Mohamed El-Shinawi 3 , Mohamed A Shaalan...
Ngày tải lên: 18/06/2014, 16:20
... domain of an alternation to a certain class of words, and ac- cordingly reduce the expansion of the analog set. 4.3 Perspectives The paradigmatic cascades model achieves quite sat- isfactory ... experimentally evaluate a new model of pronunciation by analogy: the paradigmatic cascades model. Given a pronunciation lexicon, this algorithm first extracts the most pro...
Ngày tải lên: 31/03/2014, 21:20
báo cáo hóa học:" Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences" doc
... peritoneal cavity is a common site of ovarian cancer presentation or recurrence usually accompanied by ascites [3]. Massive ascites and the associated abdominal disten- tion can cause anorexia, nausea, ... (TaKaRa Biomedicals, Japan) according to the manufacturer's instructions. The primer sequences used to amplify the human H19 transcript was (5_-ACTGGAGACTAGGGAG- GTCTCTAGCA) upst...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood" pptx
... LaVallie 1 , Deborah Young 3 , Laird Bloom 1 , Karissa Adkins 6 and Margot O'Toole* 7 Abstract Background: In preparation for potential clinical development of Ab-01, an antagonistic antibody ... Cambridge Park Drive,Cambridge, MA 02140, USA Full list of author information is available at the end of the article Arai et al. Journal of Translational Medicine 2010, 8:51 http://w...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences" potx
... used as control. The total tumor area of each bladder was determined and the mean of the total areas was calculated for each group. The Mean and SD of bladder tumor area (A) and weight (B) are ... activation was reported as a major mechanism for the IGF2 overexpression in a variety of tumors including bladder carcinoma, hepatocellular carcinoma, breast can- cer, ovarian cancer a...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Development and preliminary evaluation of a quality of life measure targeted at dementia caregivers" doc
... purposes) Health and Quality of Life Outcomes Open Access Research Development and preliminary evaluation of a quality of life measure targeted at dementia caregivers Barbara G Vickrey* 1 , Ron D Hays 2 , ... with caregiver quality -of- life scale scores were analyzed using Pearson or Spearman correlations or analysis of variance (ANOVA), as appropriate. Backwards stepwise regres...
Ngày tải lên: 18/06/2014, 18:20
báo cáo hóa học: " Development of a self-reporting tool to obtain a " docx
... (Hospital Clinic, Barcelona), J Vidal (Hospital General, Guadalajara). Milena Gobbo and Unidad de Investigación de la Fundación Española de Reumatolog a, for their technical support. Author details 1 Facultad ... complete and rapid evaluation of patients with fibromyalgia. The test intrinsically evaluates the emotional aspects: anxiety and depression, and their impact upon social aspects. I...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Development and validation of a preference based measure derived from the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) for use in cost utility analyses" doc
... respectively. Table 5 presents examples comparing the predicted values according to each model and the actual values for each health state. Validation of the preference based CAMPHOR scale A majority ... health-related quality of life in a clinical trial of respiratory rehabilitation. J Clin Epidemiol 1999, 52(3):187-92. 13. McTaggart-Cowan HM, Marra CA, Yang Y, Brazier JE, Kopec...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL" pot
... analysis of literature. Transplantation 1997, 64:1261-1273. 15. Fujisawa M, Ichikawa Y, Yoshiya K, Isotani S, Higuchi A, Nagano S, Arakawa S, Hamami G, Matsumoto O, Kamidono S: Assessment of health-related ... Comparaison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Eng J Med 1999, 341(23)...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Development and psychometric validation of a self-administered questionnaire assessing the acceptance of influenza vaccination: the Vaccinees'''' Perception of Injection (VAPI©) questionnaire" docx
... catherine.chevat@sanofipasteur.com; Muriel Viala-Danten* - mviala@mapi.fr; Carla Dias-Barbosa - cdias@mapi.fr; Van Hung Nguyen - vanhung.nguyen@sanofipasteur.com * Corresponding author Abstract Background: ... vaccinees' overall satisfac- tion with the vaccination. Competing interests Catherine Chevat and Van Hung Nguyen are sanofi pas- teur employees. Muriel Viala-Danten and Carla Dia...
Ngày tải lên: 18/06/2014, 19:20