... findings which indicated a marked increase in heart rate when S4 was engaged in activities such as: standing, brief periods of walking, and extended periods of sitting while eating (increase in ... the intensity of the activity in terms of the cardiorespiratory response. Ambulatory physiological monitoring of individuals with stroke throughout the day may provide a method...
Ngày tải lên: 19/06/2014, 10:20
... that selected sigma-2 ligands are capable of inducing apoptosis in a multitude of human and murine cancer cells lines and in animal models of cancer including pancreas cancer [12,13,15]. The mechanisms ... considerable interest in stimulating apoptosis and inhibiting survival machinery as components of cancer therapy [4-6]. Many oncogenic transformations result from the inacti...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB" pptx
... in the cancer nest; (C) and (D): the staining of CD133 on the luminal surface and the basal surface of cancer cells; (E): the staining of CD133 on budding cancer nest; (F): the staining of ... normal intestinal epithelium could be found in 72 out of 104 specimens used for this study. The CD133 expression of normal intestinal epithelium was only found in 7 out of the 72 s...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "Early detection of urothelial premalignant lesions using hexaminolevulinate fluorescence cystoscopy in high risk patients" potx
... accuracy of urinary cytology in daily practice. Cancer 1999, 87:118-128. 9. Kriegmair M, Knuchel R, Stepp H, Hofstaedter F, Hofstetter A: Detection of early bladder cancer by 5-aminolevulinic acid induced ... detection of urothelial carcinoma in situ with hexaminolevulinate fluorescence cystoscopy. J Urol 2004, 171(1):135-8. 15. Algaba F, Amin M, et al: Tumours of the urinary syst...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học:" Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer" doc
... targeting checkpoint kinase 1 (CHK1). Validation of the screening results was performed in MIA PaCa-2 and BxPC3 pancreatic cancer cells by examining the dose response of gemcitabine treatment in the ... combination of gemcitabine and CHK1 inhibitors as a potential treatment for pancreatic cancer patients. The preclinical finding of inhibition of CHK1 as a sensitizing target for...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo sinh học: "Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" pot
... +3 for increas ing intensity and “ continuity” of stain- ing of the cell membrane[17]. For quantification of Her3 staining, we scored two compartmen ts of the cell - the cell membrane, using the ... extracellular ligand-binding domain, a transmembrane domain, and an intracytoplas mic tyrosine kinase domain[3-5]. Ligand binding to these receptors induces the formation of * Correspond...
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học: " Peripheral reductive capacity is associated with cognitive performance and survival in Alzheimer''''s disease" potx
... participated in the design of the study, was involved in collection of blood samples and performed ApoE genotyping; MC participated in the design of the study, was involved in clinical examinations ... have no competing inter- ests. Cumulative survival of patients with Alzheimer's disease with low (solid line) and high (dashed line) initial AOC levelsFigure 2 Cumulative...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Measurement properties of the Dizziness Handicap Inventory by cross-sectional and longitudinal designs" docx
... studies [27], while in our study of test-retest reliabil- ity, only 27 participants were included. SDD ind estimated in sample 2 were in line with the initial findings in the DHI (SDD ≥ 18) [1]. However, ... the appointment for interview and baseline test- ing. A second test including all measures was adminis- tered about 6 months later, using the same test procedure. The same ph...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines" pptx
... Effect of imatinib on proliferation). Dasatinib in combination with chemotherapy The effect of dasatinib in combination with chemother- apy was examined in the three dasatinib responsive cell lines, ... clinical trials of dasatinib in melanoma are currently underway, including a phase I/II study of dasatinib in combination with dacarbazine http://www.clinicaltri als.gov. Con...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Adjuvant therapy of melanoma with interferon: lessons of the past decade" pot
... Trend in a single patient; (B) trend of the average value of Treg cells during HDI IV treatment; (C) Boxplot summarizing the data observed in the cohort of patients during the initial 4 weeks of ... circulating Treg cells (CD4+CD25+FoxP3+) in the blood of melanoma patients during the four weeks of HDI IV induction therapyFigure 1 A-B-C. Levels of circulating Treg cells...
Ngày tải lên: 18/06/2014, 15:20